Lipid-lowering traditional Chinese medicine monomer composition and preparation and application of lipid-lowering traditional Chinese medicine monomer composition

Abstract

The invention discloses a lipid-lowering traditional Chinese medicine monomer composition and preparation and application of the lipid-lowering traditional Chinese medicine monomer composition.The lipid-lowering traditional Chinese medicine monomer composition is prepared from quercetin-3-O-beta-D-glucuronide, hyperin, rubrofusarin-6-O-beta-D-gentiobioside, emodin-8-O-beta-D-glucoside, O-nornuciferine and armepavine in a mass ratio of (9.1 to 9.6):1:(4.2 to 4.7):(1.6 to 2.1):(2.2 to 2.7):(1.7 to 2.2). The traditional Chinese medicine monomer composition can reduce blood lipid, and especially for hypertriglyceridemia, the lipid-lowering effect is superior to that of an existing common Chinese patent medicine lipid-lowering medicine, that is Jiangzhining granule.

Description

technical field [0001] The invention relates to a lipid-lowering traditional Chinese medicine monomer composition, preparation and application. Background technique [0002] Hyperlipidemia is a common disease in today's society. It is manifested as high serum cholesterol and triglycerides, which can directly cause some diseases that seriously endanger human health, such as atherosclerosis, coronary heart disease, pancreatitis, etc. The incidence of hyperlipidemia is increasing year by year. Among the adults over 30 years old in the country, the incidence of hyperlipidemia is 10% to 20%. [0003] At present, there are many blood lipid-lowering drugs on the market. Western medicines are mostly Western medicines because of their fast onset of action and certain curative effect. Commonly used drugs such as simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol, apolipoprotein B and triglycerides, but its side effects are obvious, which...

AI Technical Summary

Problems solved by technology

The water pill is small in size, easy to swallow, and not easy to absorb moisture, but it still cannot solve the problem that the effect of reducing hyperlipidemia is not obvious and the oral dose is large

[0008] In summary, although the western medicine lipid-lowering drug simvastatin has a good lipid-lowering effect, it has obvious side effects and is not suitable for patients to take for a long time

Although the Chinese patent medicine lipid-lowering drug Jiangzhining granule and its improved dosage form have few side effects in the treatment of hyperlipidemia and are suitable for long-term consumption, there are problems such as large dosage and ineffective blood lipid-lowering effect.

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