Application of toxifolin in treating or preventing fat liquefaction and necrosis after lipofilling

Abstract

The invention discloses application of toxifolin or pharmaceutically acceptable salt thereof or a composition containing the toxifolin or the pharmaceutically acceptable salt thereof in treating or preventing infection, fat liquefaction or fat necrosis after a lipofilling operation of an individual.

Description

technical field [0001] The present invention mainly relates to the use of the pharmaceutical composition containing taxifolin in the treatment and prevention of infection, fat liquefaction and fat necrosis after fat transplantation. Background technique [0002] Fat grafting (Lipofilling) is the transplantation of the patient's autologous fat harvested through liposuction, injecting a large amount of normal saline and aseptically sucking out the fat from the thighs and other parts with high fat content, and then filling it in the desired part. Patients with congenital defects, trauma or surgical resection, including patients with third-degree burns and women undergoing lumpectomy following treatment for breast cancer, the highest incidence rate among women worldwide, can benefit from autologous fat grafting cancer. [0003] In modern medical care, the application of autologous fat transplantation is becoming more and more widespread, and people pay more and more attention t...

AI Technical Summary

Problems solved by technology

[0004] Although Danshen injection has the effect of improving the survival rate of fat grafting, the composition of Chinese herbal injection is complex and the sensitization rate is high. Researchers have not clarified the specific chemical composition that works, which limits its application

In addition, although studies have shown that tamoxifen has a certain effect of promoting fat survival, but because it is a chemotherapy drug for breast cancer, it has strong cytotoxicity, and its application is limited for patients.

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