Method for detecting adverse drug reaction signal

An adverse reaction and signal detection technology, applied in the direction of drug reference, etc., can solve the problems of suspected adverse drug reaction concealment, weak signal, large noise, etc., to achieve good promotion and application value, reduce the risk of occurrence, and accurately monitor the effect.

Pending Publication Date: 2021-04-16
山东健康医疗大数据有限公司
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Problems solved by technology

However, SRS has several disadvantages that hamper the effectiveness of signal detection
First, underreporting, underreporting, and misreporting of suspected adverse drug reactions are common in clinical practice, which means that the SRS data are not complete
Second, since SRS is a closed system of the Adverse Drug Reaction Monitoring Center and its provincial and municipal subsidiaries, it is difficult to obtain data in a timely a

Method used

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  • Method for detecting adverse drug reaction signal
  • Method for detecting adverse drug reaction signal
  • Method for detecting adverse drug reaction signal

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Embodiment

[0027] The method for detecting adverse drug reaction signals of the present invention obtains data related to adverse drug reactions in the national health information platform, and after cleaning and standardizing the data, reintegrates the data into a clinical case data warehouse, according to the preset mining algorithm and signal The detection model realizes the detection of adverse reaction risk signals.

[0028] Such as figure 1 As shown, the adverse drug reaction signal detection method specifically includes the following steps:

[0029] S1. Data processing: including data collection, data cleaning, data standardization processing and symptom extraction.

[0030] 1) Data collection is to automatically extract data related to adverse drug reactions in the national health platform through the preset interface, and obtain the patient's disease course records as a data source for data adverse drug reaction monitoring and analysis. Collect external data such as drug instr...

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Abstract

The invention discloses a method for detecting adverse drug reaction signal, and belongs to the technical field of computer software and medical informatization. According to the drug adverse reaction signal detection method, data related to adverse drug reactions in a national health information platform is obtained, the data is cleaned and normalized and then integrated into a clinical case data warehouse again, and adverse reaction risk signals are detected according to a preset mining algorithm and a signal detection model. The method for detecting the adverse drug reaction signals can timely, comprehensively and accurately monitor the safety of medical instruments on the market, processes the detected signals in time, reduces the risk of adverse drug reactions of patients, and has good popularization and application values.

Description

technical field [0001] The invention relates to the technical fields of computer software and medical informationization, and specifically provides a method for detecting adverse drug reaction signals. Background technique [0002] With the continuous development of the medical level and the continuous improvement of the public's demand for health, the issue of patient drug safety has gradually entered the public's field of vision and become one of the hot spots of global concern. Drug device safety monitoring has become an important task of regulatory authorities in various countries. In China, prescription drugs are still the most important means of treatment, in addition to the application of various Chinese patent medicines and herbal medicines, making drug safety issues more complicated and difficult to manage. In 2018, the National Adverse Drug Reaction Monitoring Network received 1.499 million adverse drug reaction / event reports, an increase of 70,000 from 1.429 mill...

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Application Information

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IPC IPC(8): G16H70/40
Inventor 钟凯左霖
Owner 山东健康医疗大数据有限公司
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