Traditional Chinese medicine composition for improving postoperative prognosis of breast cancer and application of composition

Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for improving postoperative prognosis of breast cancer and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition consists of the following raw materials in parts by weight of 15-30 parts of radix astragali, 15-30 parts of radix codonopsis, 15-30 parts of rhizoma curcumae, 15-30 parts of herba salviae chinensis, 6-12 parts of radix bupleuri and 9-15 parts of radix paeoniae alba. Aiming at syndrome differentiation and treatment of the breast cancer, all the raw materials and the weight part ratio thereof are preferably selected; the traditional Chinese medicines in a formula conform to the compatibility requirement of monarch, minister, assistant and guide, specifically, the radix codonopsis and the radix astragali are used as monarch medicines for invigorating the spleen and replenishing qi, the rhizoma curcumae and the herba salviae chinensis are used as ministerial medicines for reducing phlegm and removing stasis, the radix paeoniae alba is used as the adjuvant medicine for nourishing yin and soothing the liver, and the radix bupleuri enters the liver channel as the guide medicine; all the medicines are combined for achieving the effects of tonifying qi, strengthening the body resistance, reducing phlegm, removing stasis, soothing the liver and promoting the circulation of qi; and the whole formula combines tonification and purgation and gives consideration to both symptoms and root causes. Experimental results show that the prognosis (including OS, DFS indexes and the like) of a patient treated with the traditional Chinese medicine formula is obviously superior to that of a patient not using the traditional Chinese medicine formula, and the application prospect is wide.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for improving postoperative prognosis of breast cancer and its application. Background technique [0002] Breast cancer is a phenomenon in which breast epithelial cells proliferate uncontrollably under the action of various carcinogenic factors. In the early stage of the disease, symptoms such as breast lumps, nipple discharge, and axillary lymph node enlargement are often manifested. In the late stage, cancer cells may metastasize to distant places and cause multiple organ lesions, which directly threaten the lives of patients. Triple-negative breast cancer (TNBC) is a new breast cancer subtype proposed by scholars in recent years. This type of breast cancer has the characteristics of early onset, poor prognosis, and high susceptibility to invasion and metastasis. 70% of the cases have metastasized when they are c...

AI Technical Summary

Problems solved by technology

[0003] At present, the commonly used surgical treatment has a low success rate, while chemotherapy and radiotherapy usually have relatively large side effects, and the effect of chemical treatment is not good.

Chinese patent application: CN201110055006.5 discloses a traditional Chinese medicine for treating breast cancer and its preparation method. However, there is no report about a traditional Chinese medicine composition and its application for improving postoperative prognosis of breast cancer according to the present invention.

Images