Wet granulator for powder pharmacy

Abstract

The invention relates to the technical field of pharmacy, and discloses a wet granulator for powder pharmacy. The wet granulator comprises an inner cylinder, wherein a top cover is arranged at the top of the inner cylinder, a stirring paddle and a cutting knife are installed at the bottom and on the side wall of the inner cylinder respectively, an outer cylinder is arranged on the periphery of the inner cylinder, a material storage cavity is formed between the inner cylinder and the outer cylinder, an air inlet channel is formed in the edge of the bottom of the inner cylinder, lower filter cloth is arranged above the air inlet channel, the air inlet channel is communicated with an air pipe, and an air guide channel is formed in the inner wall of the inner cylinder. According to the invention, the air inlet channel is formed in the edge of the inner cylinder and matched with the air guide channel to guide air to flow, so that air forms a layer of air curtain on the inner wall of the inner cylinder, materials are separated from the inner wall of the inner cylinder, contact between the inner wall of the inner cylinder and the materials can be reduced, and the materials are effectively prevented from being attached to the inner wall of the inner cylinder; and the airflow applies an upward acting force to the materials, so that the materials can move and turn over upwards, and the mixing uniformity of the materials is promoted.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a wet granulator for powder pharmacy. Background technique [0002] In the wet granulation equipment, the granulation principle of the high-speed mixing granulator is: the two processes of mixing and granulation are completed in the same container, and the down-rotating stirring is adopted. The stirring paddle is installed at the bottom of the pot and forms a gap. The mixing blade can ensure that the material collides and disperses into a semi-flowing tumbling state and achieves full mixing. With the injection of the binder, the powder is gradually wetted and the shape of the material changes. The rotary movement of the chopping knife and the stirring paddle located on the horizontal axis of the pot wall produces eddy currents, which make the materials fully mixed, tumbled and collided. particles. At the same time, the extrusion, collision, friction, shearing and kneading be...

AI Technical Summary

Problems solved by technology

[0005] Aiming at the shortcomings in the use of the existing wet granulator proposed in the background technology, the present invention provides a wet granulator for powder pharmaceuticals, which has the advantages of uniform granulation and non-sticking of materials to the wall, and solves the above background The problems raised in the technology that the particles are over-cut and the material adheres to the inner wall of the barrel

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