Driving method for liquid flow of micro-fluidic chip

A technology of microfluidic chips and driving methods, applied in fluid controllers, chemical instruments and methods, and laboratory containers, etc., can solve difficult and unrealistic problems in mass production, achieve rapid mass production, and reduce production difficulty Effect

Pending Publication Date: 2021-06-08
HARBIN MEDICAL UNIVERSITY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] However, if the outlets are arranged in the same way as the outlets of the main channel, in order to avoid the mutual interference of the branch channels, it is necessary to arrange a large number of branch channel outlets, which is obviously unrealistic
[0004] At present, because PDMS has a certain degree of air p

Method used

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  • Driving method for liquid flow of micro-fluidic chip
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  • Driving method for liquid flow of micro-fluidic chip

Examples

Experimental program
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Example Embodiment

[0026] Such as Figure 1 to 4 As shown in the example, in the embodiment, in the microfluidic chip, the liquid passes from the inlet 11 through the main runway 12 to the outlet 15 of the main runner end, in order to make the flow channel branch 13 and the branch well well. The liquid is filled with a liquid, and the main flow channel 12 and the flow path branch 13 of the main chip 1 are open, and after the separator 3 is covered, the entire main chip 1 is a closed chip, except for the avoidance. Overseas, since the isolation film 3 is permeable, since the main runway 12, the flow channel branch 13 and the branch well 14 are the isolation film 3, so the liquid is also sealed in the main chip 1. On the upper, the negative pressure flow channel 21 in the upper plate 2 Unicom allocates the area of ​​the isolation film 3 above the branch well 14, thereby diffusion or negative by self-proliferation or negative after the liquid enters the flow path branch 13. The pressing causes the inspe...

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Abstract

The invention relates to a driving method for liquid flow of a micro-fluidic chip, the driving method is characterized in that in the process that liquid dispersedly flows from the main flow channel of a main chip to branches, the positions of branch wells are communicated with a negative pressure flow channel through isolating membranes, and the negative pressure flow channel is communicated with all or part of the branch wells through isolating membranes according to needs, different negative pressures are applied to the negative pressure flow channel or thrust is generated in the main flow channel according to needs so that the speed of the main flow channel entering the flow channel branch and the branch well is controlled.

Description

technical field [0001] The invention relates to a method for driving liquid flow in a microfluidic chip. Background technique [0002] The driving mode of the liquid flow in the microfluidic chip is mainly thrust or suction; in the flow channel of the microfluidic chip, there are only main channels, or when there are few main channels, the main channels are arranged with outlets, which does not affect the production and use, but when When there is a branch flow channel, when the branch does not flow out to the main channel, it is difficult for the liquid to flow to the branch flow channel and fill the branch well at the branch end of the flow channel. Gas, which can only enter when the gas is expelled; [0003] However, if the outlets are arranged in the same way as the outlets of the main channel, in order to avoid mutual interference of the branch channels, a large number of outlets of the branch channels need to be arranged, which is obviously unrealistic. [0004] At p...

Claims

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Application Information

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IPC IPC(8): B01L3/00
CPCB01L3/50273B01L3/5027B01L2400/0487B01L2400/049
Inventor 张显玉顾宇灵庞达
Owner HARBIN MEDICAL UNIVERSITY
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