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Probiotic and prebiotic compound preparation capable of relieving type 2 diabetes mellitus and preparation method thereof

A type 2 diabetes and compound preparation technology, applied in the field of diabetes treatment, can solve the problems of not being able to lower blood sugar and fail to achieve the equivalent of oral drugs for type 2 diabetes, and achieve easy access, beneficial intestinal microecological balance, and lower blood sugar levels Effect

Active Publication Date: 2021-07-16
山东晶辉生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although probiotics can improve the intestinal microecological environment, in probiotic microecological preparations, single probiotic preparations are more common, while synbiotic compound formulations that combine probiotics and prebiotics are rare. Therefore, the use of probiotics alone in the prior art cannot effectively lower blood sugar, let alone achieve the same effect as oral drugs for type 2 diabetes

Method used

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  • Probiotic and prebiotic compound preparation capable of relieving type 2 diabetes mellitus and preparation method thereof
  • Probiotic and prebiotic compound preparation capable of relieving type 2 diabetes mellitus and preparation method thereof
  • Probiotic and prebiotic compound preparation capable of relieving type 2 diabetes mellitus and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A probiotic and prebiotic compound preparation capable of alleviating type 2 diabetes, comprising the following components: a probiotic compound and a prebiotic compound; wherein the mass percent of the probiotic compound is 30%, and the mass percent of the prebiotic compound is 70%;

[0037] Among them, the probiotic components in the probiotic compound include the following 5 kinds of probiotics: Bifidobacterium longum, Bifidobacterium lactis, Lactobacillus acidophilus, Clostridium butyricum and Akkermansia muciniphila;

[0038] Wherein, the prebiotic compound is composed of natto freeze-dried powder and chicory powder.

[0039] The number of viable bacteria of the probiotic compound Bifidobacterium longum is 10 9 CFU / g, the viable count of Bifidobacterium lactis is 10 9 ~10 10 CFU / g, the number of viable Lactobacillus acidophilus is 10 9 ~10 10 CFU / g, the viable count of Clostridium butyricum is 10 9 ~10 10 CFU / g, Akkermans muciniphila is an inactivated bacter...

Embodiment 2

[0053] A probiotic and prebiotic compound preparation capable of alleviating type 2 diabetes, comprising the following components: a probiotic compound and a prebiotic compound; wherein the mass percent of the probiotic compound is 40%, and the mass percent of the prebiotic compound is 60%;

[0054] Among them, the probiotic components in the probiotic compound include the following 5 kinds of probiotics: Bifidobacterium longum, Bifidobacterium lactis, Lactobacillus acidophilus, Clostridium butyricum and Akkermansia muciniphila;

[0055] Wherein, the prebiotic compound is composed of natto freeze-dried powder and chicory powder.

[0056] The number of viable bacteria of the probiotic compound Bifidobacterium longum is 10 9 CFU / g, the viable count of Bifidobacterium lactis is 10 9 ~10 10 CFU / g, the number of viable Lactobacillus acidophilus is 10 9 ~10 10 CFU / g, the viable count of Clostridium butyricum is 10 9 ~10 10 CFU / g, Akkermans muciniphila is an inactivated bacter...

Embodiment 3

[0070] A probiotic and prebiotic compound preparation capable of alleviating type 2 diabetes, comprising the following components: a probiotic compound and a prebiotic compound; wherein the mass percent of the probiotic compound is 50%, and the mass percent of the prebiotic compound is 50%;

[0071] Among them, the probiotic components in the probiotic compound include the following 5 kinds of probiotics: Bifidobacterium longum, Bifidobacterium lactis, Lactobacillus acidophilus, Clostridium butyricum and Akkermansia muciniphila;

[0072] Wherein, the prebiotic compound is composed of natto freeze-dried powder and chicory powder.

[0073] The number of viable bacteria of the probiotic compound Bifidobacterium longum is 10 9 CFU / g, the viable count of Bifidobacterium lactis is 10 9 ~10 10 CFU / g, the number of viable Lactobacillus acidophilus is 10 9 ~10 10 CFU / g, the viable count of Clostridium butyricum is 10 9 ~10 10 CFU / g, Akkermans muciniphila is an inactivated bacter...

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Abstract

The invention relates to a probiotic and prebiotic compound preparation capable of relieving type 2 diabetes mellitus, which comprises the following components in percentage by mass: 30 to 80 percent of probiotic compound and 20 to 70 percent of prebiotic compound, the probiotic components in the probiotic compound comprise the following five types of probiotics: bifidobacterium longum, bifidobacterium lactis, lactobacillus acidophilus, clostridium butyricum and ackermann muciniophilus, and the prebiotic compound is prepared from freeze-dried natto powder and chicory powder.

Description

technical field [0001] The invention belongs to the technical field of diabetes treatment, and in particular relates to a compound preparation of probiotics and prebiotics capable of alleviating type 2 diabetes and a preparation method thereof. Background technique [0002] Type 2 diabetes (T2D) is caused by insulin resistance. The main clinical manifestations are polydipsia, polyuria, polyphagia, and weight loss. Today, it has become the world's third most serious threat to human health after cancer and cardiovascular and cerebrovascular diseases. big disease. According to the latest data released by the National Health and Family Planning Commission on November 12, 2016, the total number of diabetic patients in China has reached 100 million and will continue to grow. China has now become the country with the largest number of diabetic patients in the world. With the rapid development of bioinformatics and metagenomics, more and more studies have shown that intestinal flor...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/747A61K36/48A61K9/19A23L33/135A23L33/105A61K47/18A61K47/22A61K47/46A61P3/10A61P5/50A61K35/741A61K35/742A61K35/745
CPCA61K35/745A61K35/741A61K35/747A61K35/742A61K36/48A61K36/28A61K9/19A61K47/46A61K47/22A61K47/183A23L33/135A23L33/105A61P3/10A61P5/50A23V2002/00A23V2400/113A23V2400/533A61K2300/00A23V2200/3202A23V2200/3204A23V2200/328A23V2250/21Y02A50/30
Inventor 彭冉杨林青周昕琪于海勤孔娟
Owner 山东晶辉生物技术有限公司
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