A rapid detection device for intestinal release of coated sustained-release products

Abstract

The invention discloses a rapid detection device for intestinal release of coated slow-release products, belonging to the technical field of slow-release products, comprising a device body and an inner cylinder at the center of the device body and a multi-way tube connected to one end of the device body, wherein , the inside of the device body outside the inner cylinder is provided with extrusion chambers at equal intervals with the inner cylinder as the center of the circle, and a sampling chamber is provided between the device body and the inner cylinder at one end of the extrusion chamber, and the inside of the sampling chamber is slidingly connected There is a piston 1, and a piston rod 1 is fixed on one side of the piston 1, and a catalyst storage chamber is fixed at the end of the device body inside the multi-way pipe. In the present invention, the urine is sampled by pressing the piston rod 1 and the piston 1 in the process of reciprocating. During the sampling process, the catalyst is added synchronously. Tap the head on the position of the sampling cavity to speed up the reaction between the initiator and the urine.

Description

technical field [0001] The invention relates to the technical field of sustained-release products, in particular to a rapid detection device for intestinal release of a coated sustained-release product. Background technique [0002] Sustained-release drugs in coated sustained-release products, also known as sustained-release preparations, refer to preparations that release drugs slowly and non-constantly as required in a prescribed release medium after oral administration. Compared with the corresponding ordinary preparations, the frequency of administration is at least reduced, and Can significantly increase patient compliance or reduce drug side effects. [0003] After the coated sustained-release drug is eaten, it will be digested in the intestinal tract, so that the coated sustained-release drug is slowly released. Sampling and testing the urine discharged from animals to observe the absorption of sustained-release drugs by humans or animals. However, in the existing sa...

AI Technical Summary

Problems solved by technology

[0003] After the coated sustained-release drug is eaten, it will be digested by the intestinal tract so that the coated sustained-release drug will be released slowly. In order to detect the release rate of the coated sustained-release drug in the human or animal intestinal tract, it is necessary to test the Sampling of urine discharged by animals is used to observe the absorption of sustained-release drugs by humans or animals. However, in the existing urine sampling, it is impossible to achieve simultaneous absorption of urine The absorption of catalysts or additives has a slow fusion speed, which affects the effect of the test. At the same time, it is impossible to continuously tap the absorbed urine and catalysts or additives during the urine absorption process, so that urine and catalysts or Additives vibrate, do not speed up fusion, and are inconvenient to use

Images