Radiation dose assessment method for animal organs in particle external irradiation experiments

An experimental animal and radiation dose technology, applied in the field of radiation protection, can solve the problems that the measurement results cannot accurately reflect the size and change law of the radiation dose of organs, time-consuming and laborious, and cannot reflect the anatomical shape and position of various organs and tissues, etc., so as to improve the convenience The effect of sex and accuracy

Active Publication Date: 2021-12-17
ACADEMY OF MILITARY MEDICAL SCI
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Problems solved by technology

[0004] 1) It is necessary to make an equivalent phantom, which is time-consuming and laborious, and increases the cost of testing;
[0005] 2) The existing equivalent phantom has a simple geometric structure, which is only a cube or cylinder composed of a single substance (water or equivalent plastic), and there are no various organs and tissues in the phantom; therefore, the anatomical shape of each organ and tissue cannot be reflected The measurement results cannot accurately reflect the size and change law of the radiation dose of the organ;
[0006] 3) The measurement cycle is long and the measurement steps are cumbersome, resulting in low measurement efficiency

Method used

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  • Radiation dose assessment method for animal organs in particle external irradiation experiments
  • Radiation dose assessment method for animal organs in particle external irradiation experiments
  • Radiation dose assessment method for animal organs in particle external irradiation experiments

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Embodiment Construction

[0046] It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0047] In the prior art, the experimental method is used to measure the radiation dose at different positions of the three-dimensional water tank to represent the radiation dose of different organs. The method of using the three-dimensional water tank to represent the organism is relatively simple and rough, and the measured value cannot truly reflect the actual radiation dose of the organ. .

[0048] refer to figure 1 As shown, it is a schematic flow chart of the method for evaluating the radiation dose of experimental animal organs provided by particle external irradiation provided by an embodiment of the present invention. The method may be performed by a device, and the device may be implemented by software and / or hardware.

[0049] In this example, the method for evaluating the radiation dose of experimental an...

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Abstract

The invention relates to the field of radiation protection, and provides a method for evaluating the radiation dose of experimental animal organs by external irradiation of particles. The organ dose conversion factor can be obtained by using the digital model of the experimental animal and the simulation calculation of particle transportation, and then measuring the air kerma to determine the radiation dose of the organ. Assessment; solves the difficult problem of direct measurement of organ dose, and achieves the technical effect of improving the convenience and accuracy of organ dose assessment.

Description

technical field [0001] The invention relates to the technical field of radiation protection, and relates to a method, a device, an electronic device and a computer-readable storage medium for evaluating the radiation dose of an animal organ in a particle external irradiation experiment. Background technique [0002] With the in-depth study of the biological effects of ionizing radiation, researchers have found that the average dose of the whole body cannot meet the needs of the evaluation of biological effects; and the relationship between the biological effects of ionizing radiation and the dose is an important theoretical basis for radiation protection, that is, the medical treatment of radiation damage. Therefore, researchers usually use experimental animals (mice, rats, monkeys, etc.) to study the relationship between organ radiation dose and biological effects under particle external irradiation conditions. However, since radiation detectors cannot be placed directly in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06F30/25G06T7/00G06T7/90
CPCG06F30/25G06T7/0002G06T7/90
Inventor 张晓敏许旭谢向东宁静李大伟纪云龙
Owner ACADEMY OF MILITARY MEDICAL SCI
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