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Retina vessel measurement

A retinal blood vessel, retinal technology, applied in the field of deep learning systems, can solve problems such as vanishing gradients

Pending Publication Date: 2021-09-24
NAT UNIV OF SINGAPORE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also problems when looking to train a neural network to ensure that errors are backpropagated through the neural network - such as the vanishing gradient problem

Method used

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Embodiment Construction

[0048]Described herein is a system that utilizes deep learning to estimate retinal vascular parameters such as vessel caliber and other measurements such as, for example, vessel density. This method has been developed and tested using -10,000 retinal images from various population-based studies. It can be effectively used for large-scale scoring in population-based studies. This represents a significant time and cost savings for clinician researchers. Furthermore, the system is not limited to a specific population / ethnicity due to the breadth of the training data used. It can be used as-is for the general population. This removes geographic restrictions for clinician-researchers, enabling the system to be usefully deployed on a cloud-based platform that can be accessed from anywhere.

[0049] Embodiments of the method and system for performing the method employ preprocessing to normalize image factors. The method is thus not limited to a particular model / type of retinal fu...

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Abstract

Disclosed is a method for training a neural network to quantify the vessel caliber of retina fundus images. The method involves receiving a plurality of fundus images; pre-processing the fundus images to normalize images features of the fundus images; and training a multi-layer neural network, the neural network comprising a convolutional unit, multiple dense blocks alternating with transition units for down-sampling image features determined by the neural network, and a fully-connected unit, wherein each dense block comprises a series of cAdd units packed with multiple convolutions, and each transition layer comprises a convolution with pooling.

Description

technical field [0001] The present invention relates to a deep learning system for automatic retinal vascular measurements from fundus photographs. Background technique [0002] Clinical studies have shown that changes in retinal vascular structure are early warnings of underlying cardiovascular disease (CVD) and other conditions, such as dementia and diabetes. This is because the condition of retinal arterioles and venules mirrors the condition of blood vessels in other parts of the body. [0003] Currently, scoring of retinal photographs by human evaluators is challenged by implementation issues, evaluator availability and training, and long-term financial sustainability. Deep learning systems (DLS) have been proposed as an option for large-scale analysis of retinal images. DLS utilizes artificial intelligence and representation-learning methods to process natural raw data to identify complex structures in high-dimensional information. In contrast to traditional pattern...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06N3/02G06V10/764
CPCG06T7/0012G06T2207/20081G06T2207/20084G06T2207/30041G06N3/082G16H30/40G16H50/20G06V40/197G06V10/454G06V2201/03G06V10/82G06V10/764G06V40/193G06N3/048G06N3/045G06F18/24317
Inventor 许为宁李梦莉徐德江黄天荫张艳蕾
Owner NAT UNIV OF SINGAPORE
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