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Composition, preparation method and application thereof, preparation and application of preparation

A composition and preparation technology, applied in the fields of composition and its preparation, preparation and its application, can solve the problems of blocking IL-1 biological activity, achieve the effects of eliminating inflammation, improving the quality of life, and relieving pain

Pending Publication Date: 2021-10-01
北京中科昊盈生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] IL-1 antagonists, such as anakinra, which can block the biological activity of IL-1 by competitively inhibiting the binding of IL-1 to its receptor, also need to be administered by injection , and has the potential to cause headaches, nausea, diarrhea, and abdominal pain

Method used

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  • Composition, preparation method and application thereof, preparation and application of preparation
  • Composition, preparation method and application thereof, preparation and application of preparation
  • Composition, preparation method and application thereof, preparation and application of preparation

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1-12

[0072] Preparation Examples 1-12 respectively provide a composition. The difference between the above preparation examples lies in the weight percentage of each raw material component in the composition, as shown in Table 1.

[0073] The preparation method of the above-mentioned tissue is as follows: According to the raw material components shown in Table 1, each raw material component is fully mixed and uniform, so as to prepare the composition corresponding to each preparation example.

[0074] Each raw material component of table 1 preparation example 1-12

[0075]

Embodiment 1-12

[0078] Examples 1-12 respectively provide preparations prepared using the compositions prepared in Preparation Examples 1-12. The only difference lies in the composition used. The preparation is a tablet, wherein the composition and other raw material components are shown in Table 2.

[0079] The raw material component of the preparation of table 2 embodiment 1-12

[0080] Raw material components Example Composition (g) 18.82 Microcrystalline Cellulose (g) 28.00 Pregelatinized Corn Starch (g) 18.00 Magnesium stearate (g) 10.00 Chicken liver powder (g) 15.18 Silica (g) 10.00 Total (g) 100

[0081] The preparation method of this preparation is specifically as follows:

[0082] (1) According to the raw material components shown in Table 2, take the above-mentioned raw materials respectively;

[0083] (2) Put the above raw materials into a V-type powder mixer (model V-3B), and use the V-type powder mixer to mix for 20 mi...

Embodiment 13

[0087] This example provides a preparation made from the composition prepared in Preparation Example 11. In this preparation, the composition and other raw material components are as shown in Table 3.

[0088] The raw material component of the preparation of table 3 embodiment 13

[0089]

[0090]

[0091] The preparation method of this preparation is specifically as follows:

[0092] (1) According to the raw material components shown in Table 3, take the above-mentioned raw materials respectively;

[0093] (2) Put the composition, microcrystalline cellulose, maltodextrin, chicken liver powder and sodium tripolyphosphate in the above raw materials into a V-type powder mixer (model V-3B), and use the V-type powder mixer to mix 20min, to obtain a homogeneous mixture, and take the mixture out of the V-type powder mixer;

[0094] (3) Put the mixture obtained in step (2) into a stainless steel container, then slowly add fish oil, and stir with a stainless steel stirring rod ...

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Abstract

The invention relates to the technical field of pet food, and particularly discloses a composition, a preparation method and application thereof, a preparation and application of the preparation. The composition is prepared from the following pharmacologically acceptable raw material components: curcumin, resveratrol, piperine, astaxanthin and masticinic acid. The preparation method of the composition comprises the following steps: uniformly mixing the raw material components. The preparation comprises the composition and pharmacologically acceptable carriers and / or additives and / or feed raw materials. The composition or the preparation can be applied to medicines, foods and / or health care products for treating pet joint diseases. The pet bone joint disease treatment system can realize treatment of pet bone joint diseases, so that the life quality of pets is improved.

Description

technical field [0001] This application relates to the technical field of pet food, more specifically, it relates to a composition and its preparation method and application, a preparation and its application. Background technique [0002] Osteoarthritis is a synovial joint disease characterized by the deterioration and loss of articular cartilage with accompanying structural and functional impairment of the entire joint, including the synovium, menisci (knee), periarticular ligaments, and subchondral bone Variety. For a long time, the etiology of osteoarthritis has been considered to be the result of aging or trauma, but with the continuous improvement of people's cognition, it is currently believed that the etiology of osteoarthritis is diverse. [0003] Pathological studies of osteoarthritis have shown that the presence of inflammatory mediators in joints is directly related to osteoarthritis, among which the main inflammatory mediators are tumor necrosis factor-α (TNF-α...

Claims

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Application Information

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IPC IPC(8): A61K31/56A61P19/02A23K50/40A23K20/105A23K20/111A23K20/132A61K31/12A61K31/05A61K31/4525A61K31/122
CPCA61K31/12A61K31/05A61K31/4525A61K31/122A61K31/56A61P19/02A23K50/40A23K20/105A23K20/111A23K20/132A61K2300/00
Inventor 丁睿
Owner 北京中科昊盈生物技术有限公司
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