Bacteriostatic and/or desensitized oral paste

Abstract

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to bacteriostatic and / or desensitized oral paste. The oral paste disclosed by the invention comprises a desensitization active component, a bacteriostatic active component, an adhesive, a solid matrix, an antioxidant and a solvent. The desensitization and bacteriostasis effects of the product are jointly improved by optimizing the variety and proportion of the desensitization active components, optimizing the proportion of the desensitization active components and the bacteriostasis active components and optimizing the variety and dosage of other auxiliary materials, the problem that the active components are easy to oxidize is solved by screening the variety and dosage of the antioxidant, and the stability of the product is improved.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, in particular to an antibacterial and / or desensitizing oral paste. Background technique [0002] Dentin hypersensitivity is defined as transient pain arising from exposed dentin, usually in response to chemical, thermal, tactile, or osmotic stimuli, that cannot be explained by any other dental defect or pathology. Erosion of the outer surface of the tooth (enamel) and / or gingival recession often results in exposure of the dentinal tubules, which create pathways between the oral cavity and nerve fibers in the pulp. It has been shown in vivo that there is a pressure gradient across the dentin, which causes an outward flow of fluid. This fluid flow is disturbed or increased in response to touch, temperature (heat or cold), and osmotic stimuli (high concentrations of sugar, etc.), which are thought to result in mechanoreceptor responses of nerve fibers in the pulp (detected as pa...

AI Technical Summary

Problems solved by technology

[0005] Overcoming the deficiencies of the prior art, the present invention solves the problem that the active ingredient is easily oxidized by optimizing the screening of main and auxiliary materials and improving the formulation of the preparation, and provides a long-term stability that can effectively relieve tooth sensitivity and / or oral cavity depression. oral paste

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