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Multi-channel confluence type biological printing nozzle

A bioprinting and confluence technology, applied in the field of 3D printing, can solve the problem of uneven mixing of various materials, and achieve the effects of saving process design, high transmission efficiency and reliability, and convenient operation

Active Publication Date: 2021-10-01
HANGZHOU DIANZI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004]Aiming at the deficiencies of the prior art, the present invention proposes a multi-channel confluence bioprinting nozzle, in which the raw materials are extracted from the supply box to the In the confluence mixing area, an electromagnetic stirrer is added in the confluence mixing area to solve the problem of uneven mixing of various materials. A temperature control device is installed at the bottom of the meeting head to maintain the liquid state of the extruded material and realize layered printing output

Method used

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  • Multi-channel confluence type biological printing nozzle
  • Multi-channel confluence type biological printing nozzle
  • Multi-channel confluence type biological printing nozzle

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Embodiment Construction

[0024] Below in conjunction with accompanying drawing, the present invention will be further explained;

[0025] like figure 1 As shown, a multi-channel confluent bioprinting nozzle includes a feeding part and a confluent part.

[0026] Wherein the feeding part comprises a feeding box 10, an extraction pipeline 1, an extraction pipeline 2, an extraction pipeline 3, a micro pressure pump 11 and a confluence pipeline composed of a hose 9 connected to an L-shaped Luer connector 8. The confluence part includes a mixing box 7 , an electromagnetic stirrer 6 , a spray head 5 and a temperature control device 4 .

[0027] like figure 2 As shown, the length, width and height of the feed box 10 are 75mm, 70mm and 55mm respectively, and the length, width and height of the interior space are 50mm. The bottom of the test tube of the material is engaged to realize the fixation of the test tube. The outer diameter of the test tube outlet is 5mm, the inner diameter is 3mm, the diameter of ...

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Abstract

The invention discloses a multi-channel confluence type biological printing nozzle. The confluence type biological printing nozzle comprises a feeding part and a confluence part. Extrusion printing of biological gel liquid materials is achieved in a multi-channel confluence mode, firstly, multiple biological liquid materials are converged at one point through multiple pipelines so as to achieve liquid mixing, and multiple liquids are pumped out from the feeding part through multiple micro-pressure pumps, are collected in a confluence area through the pipelines and flow to an electromagnetic stirrer through an internal pipeline; and finally, an electromagnetic stirrer flows to the nozzle. The feeding part can keep a liquid working state of converging and extruding bio-ink through a temperature control device at the bottom of the nozzle, and realizes layered printing output of the bio-ink. A valve for controlling the extrusion actions of the micro-pressure pumps is used as a printing nozzle driving part, and then the biological 3D layered printing action is completed in a coordinate extrusion type 3D printer.

Description

technical field [0001] The invention belongs to the technical field of 3D printing, and relates to an extruding type printing nozzle, in particular to a multi-channel confluence type biological printing nozzle. Background technique [0002] Bio-3D printing technology is further developed on the basis of rapid printing. It combines cytology, computer-aided science and biomaterials, and is a new type of engineering application technology. The use of three-dimensional bioprinting technology can realize the reconstruction of tissues and organs, such as the manufacture of tissues and organs such as bone cells, skin tissues and artificial ears, but these are far from meeting the needs of human beings. Therefore, bio-3D printing technology is a hot research topic at present and even in the future, and it is one of the methods to solve the world's medical problems. [0003] In bioprinting technology, the print nozzle directly affects the quality of the finished product. After mixi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B29C64/118B29C64/209B29C64/307B29C64/295B29C64/321B33Y30/00B33Y40/00C12M3/00
CPCB29C64/118B29C64/209B29C64/307B29C64/295B29C64/321B33Y30/00B33Y40/00C12M33/00
Inventor 刘海强杨晨许依海吕明
Owner HANGZHOU DIANZI UNIV