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Immunogenic compositions and vaccines comprising african swine fever virus peptides and proteins and uses thereof

An African swine fever virus, immunogenic technology, applied in the field of veterinary vaccines, can solve problems such as unmet needs for safe ASF vaccines

Pending Publication Date: 2021-10-22
BOEHRINGER INGELHEIM VETMEDICA GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] There remains an unmet need for a safe ASF vaccine that specifically confers protection against the Georgia2007 / 1 ASFV isolate / strain

Method used

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  • Immunogenic compositions and vaccines comprising african swine fever virus peptides and proteins and uses thereof
  • Immunogenic compositions and vaccines comprising african swine fever virus peptides and proteins and uses thereof
  • Immunogenic compositions and vaccines comprising african swine fever virus peptides and proteins and uses thereof

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Embodiment Construction

[0050] The present invention solves the problems inherent in the prior art and provides a unique advance in the state of the art.

[0051] In general, the present invention relates to immunogenic compositions comprising:

[0052] (a) one, two or more ASFV peptides and / or polypeptides, preferably full-length proteins and / or immunogenic fragments thereof; and / or

[0053] (b) one, two or more ASFV oligonucleotides and / or polynucleosides encoding ASFV peptides and / or polypeptides, preferably full-length proteins and / or immunogenic fragments thereof acid and / or immunogenic fragments thereof; and / or

[0054] (c) viral or bacterial vectors, preferably recombinant and / or non-naturally occurring viral or bacterial vectors, containing peptides and / or polypeptides encoding ASFV, preferably full-length proteins and / or immunogenic fragments thereof One, two or more African swine fever virus oligonucleotides and / or polynucleotides and / or immunogenic fragments thereof; and

[0055] (d) Se...

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Abstract

The present invention relates to African swine fever virus (ASFV) peptides and / or polypeptides as well as immunogenic fragments thereof, corresponding encoding AFSV oligonucleotides and / or polynucleotides as well as immunogenic fragments thereof, immunogenic compositions, vaccines and uses thereof.

Description

[0001] sequence listing [0002] This application contains a Sequence Listing pursuant to 37 C.F.R. 1.821-1.825. The Sequence Listing accompanying this application is incorporated herein by reference in its entirety. technical field [0003] The present invention relates to the field of veterinary vaccines, and in particular to African swine fever virus peptides and / or polypeptides, preferably full-length proteins and immunogenic fragments thereof, corresponding coding African swine fever virus oligonucleotides and / or multinuclear Nucleotides and immunogenic fragments thereof, immunogenic compositions, vaccines and uses thereof. Background technique [0004] The introduction of African Swine Fever (ASF) to Georgia in 2007 and subsequent continuous spread across the European continent since spreading in Asia in 2018 proves that the disease is a major threat to the swine industry worldwide. ASF is a hemorrhagic disease of swine with mandatory declaration by the World Organi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/12A61P31/20C07K14/01C12N15/34
CPCA61K39/12A61P31/20C07K14/005A61K2039/552A61K2039/542A61K2039/54A61K2039/543C12N2710/12022C12N2710/12034A61K2039/545C07K14/01C12N15/746C12N15/86
Inventor V·尼科林E·S·蒙特F·R·冈萨雷斯L·B·卡莫斯J·A·科利亚多米根斯
Owner BOEHRINGER INGELHEIM VETMEDICA GMBH
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