The application of the biomarker combination in the preparation of a
drug for fulminant
myocarditis belongs to the field of drugs. The application is characterized in that the biomarker combination comprises
Siglec-5; the biomarker combination is further selected from the group consisting of sST2, PAI-1,
Siglec-5, CD163, CD40, P-
Cadherin, CD14, CTLA4. The application finds that the expression of the biomarker in the
plasma of a patient with fulminant
myocarditis is increased, and confirms the role of the biomarker as a
drug target in relieving and / or improving fulminant
myocarditis. The level of the biomarker can be controlled by a
drug, the diagnosis and subsequent treatment of the
disease can be more intensified, and the biomarker has great application value in clinical practice.