Antibody of fucosylated Golgi protein GP73 and use thereof

A technology of fucosylation and glycosylation, which is applied in the field of biomedicine, can solve problems such as complex operation, and achieve the effect of low detection cost and fast detection method
CN101555282AInactive Publication Date: 2009-10-14THE INST OF BASIC MEDICAL SCI OF CHINESE ACAD OF MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE INST OF BASIC MEDICAL SCI OF CHINESE ACAD OF MEDICAL SCI
Publication Date
2009-10-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to an antibody against fucosylated protein GP73, a method for preparing the antibody against the fucosylated protein GP73, a reagent for diagnosing liver cancers, a kit for diagnosing the liver cancers, application of the reagent and / or the kit to preparing products for diagnosing liver diseases and a method for preparing purified fucosylated protein GP73. Occurrence, development and metastasis of liver cancers are diagnosed by detecting the fucosylated protein GP73 or the antibody. The antibody against the fucosylated protein GP73 can be more widely used for affinity chromatography, cDNA library screening, immunologic diagnosis or pharmaceutical preparation.
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Description

technical field

[0001] The invention belongs to the field of biomedicine. Specifically, the present invention relates to an antibody against fucosylated GP73 protein, a method for preparing the antibody against fucosylated GP73 protein, a reagent for diagnosing liver cancer, A kit for diagnosing liver cancer, providing the above-mentioned reagent and / or the application of the kit in preparing products for diagnosing liver diseases, and a method for preparing and purifying fucosylated GP73 protein. Background technique

[0002] my country is a big country with hepatitis B, and the cirrhosis and hepatocellular carcinoma caused by the development of hepatitis B have brought a great burden to my country's medical resources. According to recent statistics, every two new cases of liver cancer patients in the world are One case occurred in China. Early diagnosis and treatment of liver cancer is an important task facing the field of liver science in our country.

[0003] In the 19...

Claims

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