Sample conveying device of column type detection card

Abstract

The invention relates to the field of in-vitro diagnosis and nucleic acid detection, and provides a sample conveying device of a column type detection card. The technical problem that a magnetic bead-nucleic acid complex cannot be conveyed to a nucleic acid elution amplification area of a column type detection card due to the fact that a heating device hinders an external magnetic part is mainly solved. The sample conveying device comprises a supporting body which is arranged above detection stations of detection equipment and is used for supporting a column type detection card on the detection stations, a magnetic part which is adjacent to the detection stations and can move in the vertical direction, a screw rod which is arranged on the supporting body and drives the magnetic part to move, a positioning rod which is parallel to the screw rod and is in sliding fit with the magnetic part, a driving motor of the screw rod, a blocking part which is opposite to the magnetic part and used for blocking the magnetic part from moving downwards and enabling the supporting body to be driven by the screw rod to move upwards, and a controller which is used for controlling the driving motor.

Description

technical field [0001] The invention relates to the field of in vitro diagnostic nucleic acid detection, in particular to a sample transfer device for a column detection card. Background technique [0002] The magnetic bead method is a sample delivery method used in nucleic acid detection. The magnetic bead method uses the magnetic attraction effect of the external magnetic parts and the magnetic beads in the reaction tube, and uses the external magnetic parts to drive the magnetic beads to move in the reaction tube, so as to realize the magnetic bead-nucleic acid complex from the lysate to the washing solution, and then from the washing The movement of the liquid to the reaction liquid, so as to realize the transfer of the sample. [0003] The magnetic bead method enables nucleic acid extraction, washing and amplification to be completed in a single test tube, which can simplify detection operations and avoid contamination. However, if figure 1 As shown, the amplificatio...

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Problems solved by technology

However, if figure 1 As shown, the amplification region 16 at the bottom of the detection card 17 needs to keep the shortest distance from the optical detection device 4-1 at the bottom of the detection module, so as to avoid interference while maintaining detection sensitivity, so the detection card 17 should be set as low as possible. Therefore, The first heating device 4 used to heat the elution amplification region 16 of the detection device is surrounded around the column type detection card 17, which causes that when the magnetic member 8 moves downward to the position shown by the dotted line, the first heating device 4 The device 4 will prevent the external magnetic member 8 from continuing to move downward, so that the magnetic bead-nucleic acid complex cannot be transferred to the elution amplification area 16 of the column detection card 17

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