15results about How to "Improve elution" patented technology

The invention discloses an improved efficient turbulent flow microbubble flotation device for feeding and discharging materials. Comprising an outer cylinder, an inner cylinder arranged in the outer cylinder, a stirring mechanism arranged in the outer cylinder, a feeding mechanism used for conveying raw materials into the inner cylinder, a concentrate tank located on the upper portion of the outer cylinder, a countercurrent mineralization mechanism arranged in the inner cylinder and a tailing separation mechanism connected to the bottom of the inner cylinder. Through cooperation of the sawtooth disc self-suction dispersion impeller and the false bottom structure, local area circulation can be formed, the elution effect on the surfaces of coarse particles can be enhanced, meanwhile, dispersion of heterogeneous fine silt is facilitated, and the purity of tailings is further ensured; according to the method, the flotation efficiency can be improved, and the energy consumption is greatly reduced; due to the design of the sawtooth disc self-suction dispersion impeller, gas is allowed to enter in a self-suction mode, and energy consumption of traditional air compression equipment is avoided. According to the sawtooth disc self-suction dispersion impeller, suction force brought by the vacuum effect generated by rotation of the impeller can be improved, and suction of more air is promoted.

The invention discloses a method for preparing D-calcium pantothenate from fermentation broth, and relates to the technical field of D-calcium pantothenate production.The fermentation broth of D-calcium pantothenate is subjected to flocculation and filter pressing and then enters an ultrafiltration membrane to be filtered, obtained ultrafiltration membrane clear liquid is extracted, subnatant is taken and enters a nanofiltration membrane to be concentrated, obtained concentrated liquid enters a chromatographic column to be eluted, and D-calcium pantothenate is obtained. And collecting a target component containing D-pantothenic acid, then adding a calcium chloride solution for reaction, collecting a reaction solution, cooling and crystallizing, carrying out suction filtration, washing, carrying out suction filtration again, and drying to obtain a finished product of D-calcium pantothenate. According to the method, production links are simplified, the production period is shortened, and the production efficiency is effectively improved; and the purity and yield of the product are improved, the purity is up to 99.5% or above, and the yield is up to 95% or above.

The invention belongs to the technical field of biological medicine, and particularly relates to a thalassemia detection system and kit.The thalassemia detection system comprises a collection module used for collecting a to-be-detected blood sample, an acid elution and dyeing module used for conducting acid elution and dyeing treatment on the to-be-detected blood sample, and an image collection module used for collecting images of the to-be-detected blood sample. The image acquisition module is used for carrying out image acquisition on a dyeing processing result, the image processing module is used for converting an image acquired by the image acquisition module into data information, the calculation module is used for calculating the number proportion of dyed red blood cells and the dyeing depth according to the data information, and the output module is used for displaying a calculation result. The acquisition module is connected with the acid elution and dyeing module, the acid elution and dyeing module is connected with the image acquisition module, the invention develops the thalassemia detection system, can realize rapid detection of thalassemia, and has important clinical application value.

The utility model discloses a sampling device and a detection system for fentanyl compounds. The sampling device comprises a box body, a sampling piece, a sample extraction container, a detection container and a coagulant container, the containing space is at least divided into a first storage chamber used for containing the sampling piece, a second storage chamber used for containing the sample extraction container, a third storage chamber used for containing the detection container and a fourth storage chamber used for containing the coagulant container through the partition pieces, and the sampling piece is at least used for collecting a target object on an object; the sample extraction container is provided with an inner cavity for packaging an extracting solution, the inner cavity at least can be used for accommodating a sampling piece for partially enriching a target object, a surface-enhanced Raman reagent is packaged in the detection container, and a coagulant is packaged in the coagulant container. The kit is convenient to carry, simple and convenient to operate in the detection process, high in sensitivity and suitable for on-site drug enforcement screening work of public security and customs departments.

The present invention aims to solve the technical problem that the washing and regeneration process of the oil-containing resin in the carbon fiber oil production process requires the consumption of a large amount of water and hydrochloric acid solution, and provides a new method for treating the oil-containing agent ion exchange resin, which uses an ammonia solution and a mixed acid solution to treat the oil-containing resin. The method has the characteristics of low material consumption and good washing and regeneration effect.

The present invention is a divisional application with application number 202010060063.1, and the present invention relates to the use of a lectin-macromolecular carrier coupling complex in isolating glycosylated exosomes from clinical samples, wherein the lectin-macromolecular carrier coupling complex comprises: a macromolecular carrier; and a lectin coupled to the outside of the macromolecular carrier. The lectin-macromolecular carrier coupling complex provided by the present invention can easily, quickly and accurately separate glycosylated exosomes from clinical samples, with high separation efficiency and good repeatability. The separated exosomes are in complete morphology without rupture or fragmentation, and can be directly used for glycosylated exosome liquid detection, or directly for immunological related detection, or directly extracting related nucleic acids in exosomes for genetic detection and analysis.

The chromatographic separation device comprises a shell, a heating box, a through plate and filling adsorbents, a plurality of mounting sliding blocks are symmetrically and fixedly mounted on the inner walls of the two sides of the shell, mounting sliding grooves are symmetrically formed in the side walls of the two sides of the through plate, the mounting sliding blocks are clamped and embedded in the mounting sliding grooves, a containing groove is formed in the center of the top face of the through plate, and the through plate is arranged in the containing groove. A containing groove is formed in the shell, a filling adsorbent is placed in the containing groove, a plurality of through holes are evenly formed in the bottom face of the containing groove, heat exchange cavities are symmetrically formed in the side walls of the two sides of the shell, heat exchange plates are fixedly installed on one sides of the heat exchange cavities, and air outlets are connected between the tops of the inner cavities of the heat exchange cavities and the top of the inner cavity of the shell in a communicating mode. The heating device has the advantages that the heating device is provided with the shell, the heating box, the heat exchange cavity and the heat exchange plate, when the outside temperature is low, the inner cavity of the shell can be pressurized, meanwhile, the temperature in the shell is increased, the heating speed is higher, the heating effect is better, heat waste is reduced, and the heating device is more energy-saving in use and higher in practicability.

The invention belongs to the technical field of polypeptide drug purification, and particularly relates to a polypeptide drug purification device which comprises a barrel, a cover plate is detachably fixed to the top of the barrel, and the polypeptide drug purification device further comprises a material distribution assembly, a material storage assembly and a purification assembly, and the material distribution assembly penetrates through the cover plate, extends into the barrel and is used for material distribution; the adsorption assembly is mounted in the inner cavity of the cylinder body and is used for adsorbing and purifying the materials; and the driving assembly is fixed to the top of the cover plate, the driving assembly is connected with the material distribution assembly, and the driving assembly is used for driving the material distribution assembly to rotate. The material distribution assembly is driven by the driving assembly to rotate, so that uniform material distribution on the upper side of the separation column is realized, materials can be uniformly distributed on the separation column during adsorption, the separation column is fully utilized for adsorption, eluent can be uniformly distributed on the separation column during elution, and the adsorption efficiency is improved. The sufficient contact between the eluent and the material adsorbed on the separation column is facilitated, so that the elution effect is improved.

The present invention discloses a method for determining ceramide in a sample, a product and an application thereof, and relates to the technical field of biological detection. The present invention provides a method suitable for simultaneously detecting multiple ceramides, wherein the method optimizes the mobile phase and the gradient elution program used in chromatographic elution, so that multiple ceramides can be separated and detected within 4.5 minutes, the analysis time is short, the throughput is high, and the influence of interference peaks is avoided or reduced, so that the detection signal of the ceramide to be detected can be effectively separated from the interference peak, thereby obtaining a detection result with high stability and good accuracy.

The utility model relates to the technical field of bank protection, in particular to a flexible plate making machine elution device which comprises a base, a cleaning box is fixedly connected to the upper surface of the base, a fixing assembly is arranged on the cleaning box, a cleaning assembly is arranged on the base, and the fixing assembly comprises electric sliding rails fixedly connected to the two side walls of the interior of the cleaning box; electric sliding rails are arranged on the two sides of the flexible plate, electric sliding blocks are slidably connected to the side walls of the opposite sides of the electric sliding rails, and fixing blocks are fixedly connected to the two ends of the side walls of the sides, away from the electric sliding rails, of the electric sliding blocks. According to the flexible plate cleaning device, the flexible plate is clamped and fixed, then the cleaning assembly is used for washing the flexible plate, meanwhile, the electric sliding rail is started to enable the electric sliding block to drive the rubber clamping block to move on the flexible plate, and the problems that the clamped part is blocked and is difficult to directly wash, personnel need to wash the clamped part for the second time, and the working efficiency is reduced are solved as much as possible.

The utility model relates to the technical field of antigen detection, in particular to a pathogen elution test tube, a cotton swab head can be scraped with the inner sides of a plurality of first annular scraping blades only by shifting a cotton swab up and down, so that sample pathogens on the cotton swab head are eluted, the use is more convenient, the elution effect of the pathogens is improved, and the detection efficiency is improved. The first flexible ring is used for blocking, liquid is prevented from being splashed out from the tube wall when the cotton swab is stirred, the cotton swab head can be effectively blocked, the cotton swab head is prevented from being disengaged from the tube body when the cotton swab is stirred up and down, the first flexible ring is used for stirring and guiding the cotton swab, and the cotton swab is prevented from being disengaged from the tube body. The swab swab can be inserted into the middle of the inner side of the first annular scraping blade in an accurate stroke, by arranging the first flow guide hole, when the swab swab is stirred, an extracting solution can flow up and down through the first flow guide hole, the pressure relief effect is achieved, the mixing effect of the extracting solution and a sample can be improved, the sample can be mixed in the solution more evenly and fully, and the sample quality is improved. And the detection precision is improved.

The invention discloses a microbial genetic material nucleotide extraction device and a use method thereof, and relates to the technical field of nucleotide extraction. A microbial genetic material nucleotide extraction device comprises a box body, a glass plate, a control panel and a placement groove plate, a plurality of notches are formed in the top of the placement groove plate, test tubes are inserted into the notches, an electric push rod in communication connection with the control panel is arranged at the top of the box body, and the telescopic end of the electric push rod is connected with a push plate. The push plate is located on the inner top wall of the box body, a plurality of magnetic bars in one-to-one correspondence with the test tubes are arranged at the bottom of the push plate, and a plurality of anti-take-out mechanisms in one-to-one correspondence with the test tubes are arranged at the bottom of the push plate. According to the invention, by arranging the anti-take-out mechanism, a solution adhered to the surface of the magnetic bar can be pushed into the test tube, so that the magnetic bar is prevented from taking an eluent out of the test tube, and the possibility of cross contamination among samples is also avoided while the waste of the solution is avoided.

The present invention relates to the technical field of polypeptide purification equipment, specifically a polypeptide separation and purification system, including a purification tank, a support frame is installed at the bottom end of the purification tank, a liquid adding tank and a liquid outlet pipe are connected to the outer side walls of the bottom and top of the purification tank respectively, a mounting frame is detachably installed at the middle end of the purification tank, a screen is installed on the inner side wall of the mounting frame, and the screen is located between the liquid adding tank and the liquid outlet pipe, two cylinders are symmetrically installed on the outer side wall of the purification tank, and the output ends of the two cylinders are jointly installed with a sealed bottom cover that cooperates with the purification tank, and the mounting frame is detachably connected to the top of the sealed bottom cover, and the sealed bottom cover and the bottom end of the purification tank are provided with a positioning component. The present invention can timely remind to replace the screen when the screening effect of the screen deteriorates by setting an indication component, so that the screen can be replaced in time at an appropriate time, which not only reduces the labor intensity of manual labor and avoids the waste of materials such as adsorbents, but also further improves the purification quality of the polypeptide.

The present invention provides a microfluidic chip for nucleic acid extraction and purification, belonging to the field of microfluidic technology, including: a storage part, the storage part includes a sample chamber, a reagent chamber and an isolation liquid chamber; a nucleic acid extraction and purification part, the nucleic acid extraction and purification part is arranged on the side away from the rotation center compared to the storage part, the nucleic acid extraction and purification part includes at least two working chambers and a sealing chamber arranged on the side of the working chamber close to the rotation center, the different working chambers are connected by a first valve body arranged in the sealing chamber, and the distal end of the sample chamber, the reagent chamber and the isolation liquid chamber are connected to the proximal end of the sealing chamber by a second valve body. Centrifugal force and Euler force are relied on to achieve complete filling and release of liquid reagents and mixing with magnetic beads, and mineral oil is combined with a unique chamber structure and a segmented pressure-blocking valve structure design to ensure that the liquid components between chambers are isolated from each other, ensuring a good nucleic acid extraction effect under the premise of high space utilization.

This utility model belongs to the field of coal chemical wastewater pretreatment technology, and discloses a resource substance recovery system for coal chemical wastewater, including an adsorption separation system, an adsorption material regeneration system, and a recovery and regeneration system. The adsorption separation system is used to adsorb and separate resource substances in the wastewater to be treated using adsorption materials. The resource substances in the wastewater to be treated include oils and phenols. The adsorption material regeneration system is used to regenerate the adsorption material using a regeneration solution. The recovery and regeneration system is used to regenerate the regeneration solution and separate and recover the adsorbed resource substances. This utility model achieves efficient separation of oils and phenols by filling the adsorption separation device with adsorption material. The adsorption material regeneration system provides a regeneration solution to the adsorption separation device to achieve elution and regeneration of the adsorption material, thereby realizing the recycling of the adsorption material and effectively reducing the recycling and treatment cost.