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Compound cortex phellodendri medicinal preparation, preparation method and application

The technology of a pharmaceutical preparation and Cortex Phellodendri, applied in the field of medicine, can solve the problems of difficult bacteriostatic effect, bitter taste, etc., and achieve the effects of significant curative effect, small dosage, and prevention of bacterial infection in the oral cavity.

Pending Publication Date: 2021-11-26
SHANDONG HANFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The invention provides a compound Phellodendron phellodendron pharmaceutical preparation, preparation method and application. The composition is improved on the basis of the existing compound Phellodendron phellodendri varnish, and a medicine with good therapeutic effect on oral ulcers caused by Behcet's disease is obtained. It has a remarkable curative effect, solves the problems of the existing compound Phellodendron phellodendron liquid paint with bitter taste, is difficult to take orally and has poor antibacterial effect, and provides a new way for the treatment of oral ulcers caused by Behcet's disease

Method used

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  • Compound cortex phellodendri medicinal preparation, preparation method and application
  • Compound cortex phellodendri medicinal preparation, preparation method and application
  • Compound cortex phellodendri medicinal preparation, preparation method and application

Examples

Experimental program
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Effect test

Embodiment 1

[0028] A compound Phellodendron phellodendron pharmaceutical preparation is made up of the following components by weight:

[0029] 8g Forsythia, 4g Cortex Phellodendri, 4g Honeysuckle, 4g Dandelion, 0.24g Centipede, 0.3g Menthol, 2.5g 20% ​​Chlorhexidine Gluconate, 0.1g Steviol Glycoside, 2g Tween 80, 10g Propylene Glycol.

[0030] The preparation method of above-mentioned compound Phellodendron Phellodendri medicinal preparation adopts following steps to prepare:

[0031] (1) Preparation of menthol propylene glycol solution: according to the aforementioned weight, take propylene glycol and add menthol, heat and stir at 50-80° C. to dissolve, cool to normal temperature, and set aside;

[0032] (2) According to the aforementioned weight, take the above five flavor components, add water to decoct three times, add 10 times the amount of the total drug weight for 1 hour, add 8 times the amount of water for 45 minutes, and add 8 times the amount of water for 45 minutes. Add 6 tim...

Embodiment 2

[0036] This compound phellodendron phellodendron medicinal preparation is made of the following components by weight:

[0037] 5g forsythia, 2g cork, 2g honeysuckle, 2g dandelion, 0.1g centipede, 0.2g menthol, 20% chlorhexidine gluconate 2g, 0.1g steviol glycoside, 0.5g Tween 80, 5g propylene glycol.

[0038] The preparation method is the same as the preparation steps of Example 1, and will not be described in detail here.

Embodiment 3

[0040] This compound phellodendron phellodendron medicinal preparation is made of the following components by weight:

[0041] 10g forsythia, 10g cork, 10g honeysuckle, 10g dandelion, 0.5g centipede, 0.5g menthol, 10g 20% ​​chlorhexidine gluconate, 0.5g steviol glycoside, 5g Tween 80, 15g propylene glycol.

[0042] The preparation method is the same as the preparation steps of Example 1, and will not be described in detail here.

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Abstract

The invention relates to the technical field of medicine, and particularly relates to a compound cortex phellodendri medicinal preparation, a preparation method and application. The compound cortex phellodendri medicinal preparation is prepared from fructus forsythiae, cortex phellodendri, lonicera japonica, dandelion, centipede, menthol, 20% chlorhexidine gluconate, stevioside, Tween 80 and propylene glycol. According to the compound cortex phellodendri medicinal preparation, the formula is improved on the basis of an existing compound cortex phellodendri liquid liniment, a medicine with a good treatment effect on oral ulcer caused by the behcet disease is obtained, the curative effect is remarkable, and the problems that the existing compound cortex phellodendri liquid liniment is bitter in taste, difficult to take orally and poor in antibacterial effect are solved.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a compound phellodendron phellodendron medicinal preparation, preparation method and application. Background technique [0002] Behcet's disease is an autoimmune disease characterized by oral mucosal ulcers and eye, genital, and skin lesions occurring simultaneously or successively. Among them, oral ulcers are the most basic lesions, which are seen in more than 98% of patients. And it is the first symptom of this disease. Ulcers can occur anywhere in the oral cavity and pharynx, such as the palate, buccal mucosa, gums, tongue, inner lips and throat. The etiology and pathogenesis of the disease are not very clear, and modern medicine believes that it may be related to various factors such as infection, heredity, and immunity. Topical application of glucocorticoid cream, Bingboron powder and Xilei powder etc. treatment. In the clinical diagnosis of traditional Chinese medicine,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/12A61K47/18A61P1/02A61P37/02A61P31/04A61K31/045A61K31/155A61K35/648
CPCA61K36/634A61K36/756A61K36/355A61K36/288A61K35/648A61K31/045A61K31/155A61K9/006A61K9/12A61K47/18A61P1/02A61P37/02A61P31/04A61K2236/331A61K2236/55A61K2236/39A61K2300/00
Inventor 许庆友马河徐凤霞秦承雪王璐
Owner SHANDONG HANFANG PHARMA
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