Method for establishing upper respiratory tract-tracheal tree combined model based on three-dimensional reconstruction

Abstract

The invention discloses a method for establishing an upper respiratory tract-tracheal tree combined model based on three-dimensional reconstruction, and belongs to the technical field of respiratory tract three-dimensional reconstruction, and the method comprises the steps of firstly obtaining a CT medical image of a real human body, importing image data into image analysis software, and adjusting various display parameters; manually correcting and drawing a human body target area mask by applying a threshold method developed by software and an area growing function in combination with anatomical features; segmenting Human respiratory tract tissues: nasal cavities including nasal vestibules, olfactory regions, paranasal sinuses and other regions; the oral cavity that comprises two lips, two cheeks, a hard palate, a soft palate and the like; the throat pipe that comprises areas such as an anorexia cartilage, a thyroid cartilage and an annular cartilage; and the trachea-bronchus that comprises a bronchus area from a main bronchus to a six-stage airway, thus a human body upper respiratory tract-trachea tree combined model is reconstructed on the basis. The human body upper respiratory tract-tracheal tree combined model established by the establishment method has the characteristics of individuation, close to a real arrangement structure of a human body and the like.

Description

technical field [0001] The invention belongs to the technical field of three-dimensional reconstruction of the respiratory tract, and more particularly relates to a method for establishing a combined upper respiratory tract-tracheal tree model based on three-dimensional reconstruction. Background technique [0002] According to epidemiological and case studies, most lung diseases are related to occupations and environments exposed to environmental aerosol pollutants. Inhalation of pharmaceutical aerosols is a modern approach to target lung tumors and combat respiratory diseases. Obviously, the real and effective simulation of lung aerosol dynamics can provide an important reference for understanding the deposition of toxic particles and the treatment of related lung diseases. However, limited by the constraints of current computing resources, it is impossible to simulate the transient three-dimensional flow field of all 23 levels of bronchi after aerosol inhalation. Theref...

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Problems solved by technology

[0003] In view of the above defects or improvement needs of the prior art, the present invention provides a method for establishing a combined model of the upper respiratory tract and tracheal tree based on three-dimensional reconstruction, thereby solving the problem that the existing simplified deposition prediction model is difficult to predict the delivery and deposition of drug aerosols in the respiratory tract regular technical issues

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