Porous silica gel glaucoma drainage device

A porous silica gel and glaucoma technology, applied in the field of medical devices, can solve the problems of endplate fibrous capsule wrapping, filtration tract scarring, drainage device displacement, etc., so as to slow down the formation of fibrous vesicles, prevent scarring, and solve displacement. Effect

Pending Publication Date: 2022-01-14
SHANDONG BRANDEN MEDICAL DEVICE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004]However, the existing glaucoma drainage devices often have problems such as displacement of the drainage device, scarring of the filtering tract, and encapsulation of the fibrous capsule of the endplate, resulting in the failure of the drainage device to drain , poor drainage of aqueous humor, increased intraocular pressure, and ultimately failed surgery. Therefore, a drainage device for the treatment of refractory glaucoma is urgently needed to solve the technical problems of drainage device displacement, scarring and fibrous cystic cavity wrapping during glaucoma treatment.

Method used

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  • Porous silica gel glaucoma drainage device
  • Porous silica gel glaucoma drainage device
  • Porous silica gel glaucoma drainage device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: as figure 1 As shown, the drainage tube of the porous silicone glaucoma drainage device can have an outer diameter of 0.5 mm and an inner diameter of 0.3 mm. The aqueous humor discharge one-way valve is composed of two silica gel membranes, and the specifications can be 8 mm in length and 7 mm in width. The specification of the fixing hole can be selected to have an inner diameter of 1.6 mm. The porous silicone tube has a diameter of 1.2 mm and an inner diameter of 1 mm. The inner diameter of the drainage hole is 0.4 mm, and the concentration of the mitomycin C drug coating on the inner wall of the drainage hole may be 0.1 mg / mL. The curvature of the porous curved plate conforms to the curvature of the limbus of the corneosclera, the surface area is 180 mm2, and the thickness is 1 mm.

Embodiment 2

[0033] Embodiment 2: as figure 1 As shown, the drainage tube of the porous silicone glaucoma drainage device can have an outer diameter of 0.5 mm and an inner diameter of 0.3 mm. The aqueous humor discharge one-way valve is composed of two silica gel membranes, and the specifications can be 8 mm in length and 7 mm in width. The specification of the fixing hole can be selected as having an inner diameter of 2 mm. The porous silicone tube has a diameter of 1.8 mm and an inner diameter of 1.6 mm. The inner diameter of the drainage hole is 0.4 mm, and the concentration of the mitomycin C drug coating on the inner wall of the drainage hole may be 0.1 mg / mL. The curvature of the porous curved plate conforms to the curvature of the limbus of the corneosclera, the surface area is 180 mm2, and the thickness is 1 mm.

Embodiment 3

[0034] Embodiment 3: as figure 1 As shown, the drainage tube of the porous silicone glaucoma drainage device can have an outer diameter of 0.5 mm and an inner diameter of 0.3 mm. The aqueous humor discharge one-way valve is composed of two silica gel membranes, and the specifications can be 8 mm in length and 7 mm in width. The specification of the fixing hole can be selected to have an inner diameter of 2.4 mm. The porous silicone tube has a diameter of 2.2 mm and an inner diameter of 2 mm. The inner diameter of the drainage hole is 0.4 mm, and the concentration of the mitomycin C drug coating on the inner wall of the drainage hole may be 0.1 mg / mL. The curvature of the porous curved plate conforms to the curvature of the limbus of the corneosclera, the surface area is 180 mm2, and the thickness is 1 mm.

[0035] The specific test results are shown in Table 1:

[0036] Table 1 Proportion of tissue ingrowth depth at different time after operation

[0037] According to ...

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Abstract

The invention relates to a porous silica gel glaucoma drainage device. The device consists of a drainage tube and an aqueous humor discharge unit, wherein the aqueous humor discharge unit consists of an aqueous humor discharge one-way valve and a porous arc-shaped plate; the aqueous humor discharge one-way valve is connected with the drainage tube; and fixing holes and drainage holes are distributed in the porous arc-shaped plate. Porous silica gel tubes are embedded in the fixing holes, so that tissue cells can grow into the holes easily, a good fixing effect can be provided for a glaucoma drainage device, and the problem of displacement of the drainage device is solved; and the inner walls of the drainage holes are coated with mitomycin C medicine coatings, so that tissue scarring in a filtering channel can be solved, and cyst cavity wrapping is prevented.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a porous silicone glaucoma drainage device. Background technique [0002] Glaucoma (glaucoma) is one of the three major eye blinding diseases in the world, and it is an irreversible eye damage disease. Glaucoma is mainly caused by the increase of intraocular pressure caused by poor aqueous humor circulation, manifested as increased intraocular pressure, visual field defect, decreased vision and optic disc atrophy, which seriously threatens the health of patients. At present, the first choice for the treatment of refractory glaucoma at home and abroad is drainage implantation. [0003] There are mainly three types of drainage devices for glaucoma drainage implantation: (1) The glaucoma drainage valve consists of a silicone tube and a silicone endplate, and the silicone tube is inserted into the anterior chamber (or in some cases Insert into the vitreous cavity or ciliary...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F9/007
CPCA61F9/00736A61F9/00781
Inventor 张海军蔡田雨韩真真袁坤山
Owner SHANDONG BRANDEN MEDICAL DEVICE
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