The invention relates to a disposable ligation device for anorectal hemorrhoids. Particularly, multiple hemorrhoids can be ligated, and replaceable rotatable ligation assemblies can also be selected for the hemorrhoids different in degree, internal rectal prolapse and other anorectal diseases to achieve the best treatment effect. The device comprises a rotatable ligation assembly, a ligation assembly connection fixing device, a negative pressure tube assembly, a trigger and a shell; the rotatable ligation assembly comprises an elastic thread loop, a push tube, a suction tube, a long tube, a rotary knob and an elastic thread component; the shell is composed of a left shell body and a right shell body, the front portions in the left shell body and the right shell body are internally provided with locking hoop guide grooves and spring positioning baffles, and the middles in the left shell body and the right shell body are arranged in a connection fixing device mounting groove; the ligation assembly connection fixing device comprises a trigger tube, a locking hoop, a spring, a spring base, a catch button, a catch button connector, a push button and a seal ring; the negative pressure tube assembly comprises a two-way tube, a three-way tube, an air tube connector, a silicone tube and a negative switch.