Device for predicting CAP risk of ITP patient and system and application thereof

A risk, patient technology, applied in the prediction device, system and application field of the risk of CAP in ITP patients, which can solve the problems of non-recognized ITP patient prediction model and so on

Pending Publication Date: 2022-02-22
PEOPLES HOSPITAL PEKING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the high risk factors of pneumonia in ITP patients, and there is no recognized prediction model for the risk of CAP in ITP patients.

Method used

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  • Device for predicting CAP risk of ITP patient and system and application thereof
  • Device for predicting CAP risk of ITP patient and system and application thereof
  • Device for predicting CAP risk of ITP patient and system and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Example 1. Development and verification of the ACPA scoring model for predicting the risk of CAP in ITP patients

[0056] The present invention has developed and verified the ACPA integral model for predicting the risk of CAP in ITP patients, the process is as follows figure 1 shown. Specific steps are as follows:

[0057] 1. Patient samples and research methods for developing an ACPA scoring model for predicting the risk of CAP in ITP patients

[0058] 1. Patient samples

[0059] The patient samples in this study included a multi-center retrospective cohort study including 10 large clinical centers in China from 2002 to 2019 ( figure 1 ), the target population is adult patients with primary ITP without splenectomy (age greater than or equal to 10 years old). Patients diagnosed with connective tissue disease, tumor (solid tumor or leukemia), primary immunodeficiency, liver insufficiency and other diseases that can cause secondary thrombocytopenia were excluded from ...

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PUM

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Abstract

The invention discloses a device for predicting the CAP risk of an ITP patient and a system and an application thereof. The device comprises the following processing modules: a data input module, a data recording module, a data assignment module, a data calculation module, a data grouping module and a conclusion output module. The system for predicting the CAP risk of the ITP patient comprises a device for predicting the CAP risk of the ITP patient, platelet counting equipment and lymphocyte number measuring equipment. By means of the device for predicting the CAP risk of the ITP patient or the system , the high-risk patient can be recognized in the early stage only through medical history inquiry and whole blood cell examination, and timely treatment is provided.

Description

technical field [0001] The invention relates to a device, system and application for predicting the risk of CAP in ITP patients. Background technique [0002] Essential thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by antibody-mediated platelet destruction and decreased platelet production due to platelet production disorders. Glucocorticoids are the first-line treatment for ITP, and intravenous gamma globulin (IVIg) is considered when patients are in an emergency or are intolerant to steroids. Rituximab, thrombopoietin (TPO) receptor agonists, immunosuppressants and splenectomy are the second-line treatments for ITP. According to reports, the overall response rate of initial treatment of ITP patients can reach 90%, however, many patients will relapse once hormone or IVIg is stopped, which means that ITP patients need chronic or continuous treatment. Due to the immune disorder of the ITP disease itself and the immunosuppression caused by long-term...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/30G16H50/50
CPCG16H50/30G16H50/50
Inventor 张晓辉黄晓军吴冶君皇秋莎赵芃陈琪刘凤琪朱晓璐何云付海霞
Owner PEOPLES HOSPITAL PEKING UNIV
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