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Tablet online sampling detection control system and tablet quality detection system

A detection control system, tablet technology, applied in measuring devices, manufacturing tools, instruments, etc., can solve problems such as increasing failure rate, time lag, individual operation differences, and inability to detect quality abnormalities in time, and achieve scientific detection. Reasonable and improve the effect of abnormal situation

Pending Publication Date: 2022-03-04
JIANGZHONG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing tablet quality control relies on laboratory tablet weight and hardness test results, manually adjust tablet machine parameters to control tablet weight and hardness based on experience, there is a certain time lag and individual operation differences
[0004] There are at least the following technical problems in the quality control of traditional drug tablet compression: usually the quality control of tablet compression mainly relies on sampling offline detection, manual adjustment of tablet machine parameters to control tablet weight and hardness, resulting in quality abnormalities that cannot be detected in time, and manual adjustment of compression There is a certain lag in the parameters of the tablet machine, and there is a risk of an increase in the unqualified rate and unqualified drugs flowing into the next process

Method used

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  • Tablet online sampling detection control system and tablet quality detection system
  • Tablet online sampling detection control system and tablet quality detection system
  • Tablet online sampling detection control system and tablet quality detection system

Examples

Experimental program
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Effect test

Embodiment 1

[0045] Please refer to figure 1 , this embodiment provides an online tablet sampling and testing control system 100, which is suitable for sampling and testing the tablets discharged from the tablet press and controlling the operating parameters of the tablet press according to the test results. Specifically, the tablet online sampling detection control system 100 of the present application includes an automatic sampling mechanism 110, a group weighing mechanism 120, a single particle detection mechanism 130 and a control mechanism 140, and the discharge port of the automatic sampling mechanism 110 is connected to the group weighing mechanism 120. The feed port is connected with the feed port of the single-grain detection mechanism 130, the unqualified product discharge port of the group weighing mechanism 120 is connected with the feed port of the single-grain detection mechanism 130, the automatic sampling mechanism 110, the group weighing mechanism 120, the single-grain The...

Embodiment 2

[0062] see Figure 7 , this embodiment provides a tablet quality detection system, which includes the tablet online sampling detection control system 100 of Embodiment 1.

[0063] Further, the tablet quality inspection system of this embodiment also includes a tablet press, a device to be released, a finished product material barrel, a waste material barrel, a tablet screening machine and a metal detector.

[0064] The tablet press is equipped with a self-inspection mechanism, and the self-inspection mechanism is equipped with a self-inspection qualified pipeline and a self-inspection unqualified pipeline. The self-inspection qualified pipeline is connected to the finished material barrel, and the self-inspection unqualified pipeline is connected to the waste barrel;

[0065] The tablet on-line sampling detection control system 100 is communicated with the self-inspection qualified pipeline and conducts sampling inspection on the tablets on the self-inspection qualified pipeli...

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Abstract

The embodiment of the invention provides a tablet online sampling detection control system and a tablet quality detection system, and relates to the field of pharmaceutical equipment. The tablet online sampling detection control system comprises an automatic sampling mechanism, a group weighing mechanism, a single-particle detection mechanism and a control mechanism, a discharging port of the automatic sampling machine is communicated with a feeding port of the assembling and weighing mechanism and a feeding port of the single-grain detection mechanism, an unqualified product discharging port of the assembling and weighing mechanism is communicated with a feeding port of the single-grain detection mechanism, and the automatic sampling machine, the assembling and weighing mechanism, the single-grain detection mechanism and the tablet press are electrically connected with the control mechanism. Automatic sampling and sample introduction can be realized, combination of a group weighing mode and single-particle detection is realized, and individual, overall and average value change trends are considered while tabletting quality control is realized, so that the method is more scientific and reasonable. And the control mechanism receives signals fed back by the automatic sampling mechanism, the group weighing mechanism and the single grain detection mechanism and feeds the signals back to the tablet press, so that real-time adjustment on operating parameters of the tablet press is realized.

Description

technical field [0001] The invention relates to the field of pharmaceutical equipment, in particular to a tablet online sampling detection control system and a tablet quality detection system. Background technique [0002] Traditional drug tablet quality control relies on manual sampling, and judges the tablet quality status of the product based on laboratory test results. When abnormal conditions occur, it relies on manual adjustment of tablet machine parameters to ensure that qualified tablets are produced. [0003] Existing tablet pressing mainly controls quality indicators such as tablet weight and hardness. The tablet weight depends on the electronic balance in the laboratory, and the hardness tester in the laboratory is used to control product quality. The existing quality control of tablet pressing relies on laboratory tablet weight and hardness test results, and manually adjusts the parameters of the tablet press machine to control tablet weight and hardness based on...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01D21/02B30B15/26
CPCG01D21/02B30B15/26
Inventor 刘旭海张细和钟志坚彭伟王谷洪朱明辉金保熊静肖金发付鹏亮费翼城乐军华罗勇黎平
Owner JIANGZHONG PHARMA
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