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Electromagnetic composite biomacromolecule separation technology and equipment

A biological macromolecule and electromagnetic compound technology, which is applied in the preparation of sugar derivatives, sugar derivatives, sugar derivatives, etc., can solve the problems of leakage and incomplete separation, and achieve improved separation accuracy, good use effect and reasonable design Effect

Pending Publication Date: 2022-04-05
SHANGHAI TANON LIFE SCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The direction of movement outside the figure of eight will lead to incomplete separation, and accidents such as leakage are prone to occur

Method used

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  • Electromagnetic composite biomacromolecule separation technology and equipment
  • Electromagnetic composite biomacromolecule separation technology and equipment
  • Electromagnetic composite biomacromolecule separation technology and equipment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] An electromagnetic composite biological macromolecule separation technology, the simplest technology is to directly increase the strong electromagnetic field in the electrophoresis tank of the existing electrophoresis equipment, using large-scale magnetic field generating components, such as figure 2 , 3 As shown, the magnetic field generating component includes an induction coil 14 and a magnetic field conductor 13 disposed in the induction coil 14 . The induction coil includes a metal coil, a current regulator 12 and a switch 15 connected in series with the metal coil, and the switch 15 and the current regulator 12 are respectively connected to two poles of an external DC power supply.

[0031] The gel 3 and the electric field generating equipment in the electrophoresis tank are all existing technologies, and will not be described in detail in this embodiment.

[0032] The electric field generated by direct current is a special substance existing in the space around...

Embodiment 2

[0038] Such as figure 2 , Figure 4 As shown, an electromagnetic composite biomacromolecule separation technology is greatly improved in the existing equipment, which is more practical and has better effect. The specific improvement is: the gel in the electrophoresis tank 1 is divided into several segmented areas in parallel along the material separation direction, and each segmented area has an independent electric field and magnetic field. The electric field and magnetic field in all segmented areas are controllable; the electric field and magnetic field work together to drive the biomacromolecules to move, and ensure that the moving directions of the biomacromolecules in all segmented areas are parallel.

[0039]The electric fields are segmented electric fields respectively output by the same DC power supply through several terminal assemblies, and the terminal assemblies correspond to the segmented areas one by one. The magnetic field is a combined magnetic field, inclu...

Embodiment 3

[0045] This embodiment is based on Embodiment 2, and the magnetic field generating components are optimized as required.

[0046] Under the condition that other technologies remain unchanged, the magnetic field generating component includes one induction coil or two induction coils.

[0047] When the magnetic force of the magnetic field is required to be small, there is only one induction coil, and the induction coil is installed on the corresponding electrophoresis tank at one end of the segmented area.

[0048] When the magnetic force of the magnetic field is required to be large, there are two induction coils, and the two induction coils are installed on the corresponding electrophoresis tanks at both ends of the segmented area, and the directions of the magnetic fields are consistent. All induction coils are identical, with the same number of turns and the same winding direction.

[0049] When in use, the electric field movement direction 4 of the biomacromolecule 2 is al...

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PUM

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Abstract

According to the electromagnetic composite biomacromolecule separation technology, gel in an electrophoresis tank is divided into a plurality of segmented areas in parallel in the material separation direction, and an independent electric field and an independent magnetic field are arranged in each segmented area; the electric fields and the magnetic fields in all the segmented areas are controllable; the electric field and the magnetic field jointly act to drive the biomacromolecules to move, and it is guaranteed that the moving directions of the biomacromolecules in all the segmented areas are parallel. The magnetic field generator is additionally arranged in the electrophoresis tank, linear motion is kept in the biomacromolecule separation process by utilizing the characteristic that the magnetic field acts on biomacromolecule motion, direction deviation is avoided, the design is reasonable, the structure is simple, the actual use effect is good, and the application of the magnetic field to biomacromolecule separation is pioneered.

Description

technical field [0001] The invention relates to the technical field of biomacromolecule separation, in particular to an electromagnetic composite biomacromolecule separation technology and equipment. Background technique [0002] The electrophoresis tank is often used in biomedical biomacromolecule separation experiments. The principle is: the terminals of the electrophoresis tank include positive and negative electrodes, and the positive and negative electrodes are respectively connected to the positive and negative output terminals of the DC power supply. The anode electrode inside the electrophoresis tank, various gels with space grid steric structure, the cathode electrode in the electrophoresis tank, the relationship between the cathode end of the submerged gel and the cathode electrode of the electrophoresis tank, and the anode end of the submerged gel and the anode electrode of the electrophoresis tank. Buffers with conductive properties form the DC circuit loop. [...

Claims

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Application Information

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IPC IPC(8): C07K1/36C07K1/26C07K1/14C07H21/04C07H21/02C07H1/06
Inventor 孟诚卫
Owner SHANGHAI TANON LIFE SCI CO LTD
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