Device and method for obtaining outflow effect parameter based on perfusion image

Abstract

The invention discloses a device and method for obtaining outflow effect parameters based on perfusion images, and the method comprises the detection steps: continuously collecting the perfusion images and an artery input function after perfusion, aligning the perfusion images of a subsequent time phase with a first time phase image, and removing artifacts and images which cannot be aligned; the method comprises the following steps of: acquiring a perfusion image, converting the perfusion image into a contrast agent concentration image, acquiring a residual function of each pixel point in the perfusion image based on an Indicator-Dilution principle, and calculating an outflow effect parameter, and measuring the outflow effect of the tissue by fully utilizing a residual function curve in a quantitative post-processing process of the MR or CT perfusion image. The residual function curve reflects the response of the tissue to the pulse blood flow (containing the contrast agent), so that the descending part of the residual function is the direct response of the outflow effect of the contrast agent in perfusion, and the measured outflow effect parameter is more accurate than the direct use of the dynamic perfusion curve.

Description

technical field

[0001] The invention relates to the technical field of image processing, in particular to a device and method for obtaining outflow effect parameters based on perfusion images. Background technique

[0002] Dynamic Contrast Enhanced Imaging (DCE, Dynamic Contrast Enhanced) and Dynamic Susceptibility Contrast Imaging (DSC, Dynamic Susceptibility Constrast) are two commonly used methods for NMR to measure perfusion. DSC perfusion imaging begins with an intravenous bolus of gadolinium chelate followed by rapid acquisition of a series of gradient-echo or spin-echo images of the organ of interest. When gadolinium chelate passes through the local circulation for the first time, it remains largely confined to the intravascular space. Due to the paramagnetic characteristics of the gadolinium base, the gadolinium base produces local magnetic field disturbance around the blood vessel when the bolus injection passes, and the T2 (T2*) dephasing causes signal loss. Vari...

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