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Apparatus and method for capturing image data

A technology for capturing images and image data, applied in fluorescence/phosphorescence, instruments, optical components, etc., to achieve good spatial resolution, good time resolution, and sensitivity

Pending Publication Date: 2022-05-06
CARL ZEISS MICROSCOPY GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the disadvantage is that each microlens group only uses a part of the aperture

Method used

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  • Apparatus and method for capturing image data
  • Apparatus and method for capturing image data
  • Apparatus and method for capturing image data

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Embodiment Construction

[0087] In a general arrangement of the apparatus 1 according to the invention, there are means 2 for separating the detection radiation along the beam path in the form of a beam splitter (beam splitter 2), whose function is to have a first detector 4 and arranged in The detection radiation is split between the first detection path 3 of the first microlens array 5 upstream thereof and the second detection path 6 with the second detector 7 and the second microlens array 8 arranged upstream thereof. Microlens arrays 5 and 8 are each arranged in a pupil. If optical lenses 9 are specified in the exemplary embodiment, they optionally also represent a corresponding combination of optical elements (lens systems).

[0088] The first detector 4 allows its first spatial resolution to be higher than the spatial resolution of the second detector 7 . The temporal resolution of the first detector 4 (slow camera) is lower than that of the second detector 7 (fast camera). In a further embodi...

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Abstract

The invention relates to a device for capturing image data, comprising a detection beam path and means for separating detection radiation between a first detection path and a second detection path. A detector is located in each detection path. The microlens array is disposed upstream of the at least one detector. The first detector has a first spatial resolution, the second detector has a second spatial resolution, and the first spatial resolution is higher than the second spatial resolution. Additionally or alternatively, the first detector has a first temporal resolution, the second detector has a second temporal resolution, and the first temporal resolution is lower than the second temporal resolution. There is an evaluation unit for evaluating the captured image data of the first and second detectors, which is configured such that the image data captured by each detector is computationally combined together to form a resulting image of the three-dimensional analysis. The invention also relates to a microscope comprising a device according to the invention, and to a method of capturing image data.

Description

technical field [0001] The present invention relates to an apparatus and method for capturing image data. Background technique [0002] Modern microscopy increasingly focuses on the rapid capture of three-dimensional sample volumes. An important application here is the measurement of neural signals in neural cell networks. These networks are spread across the brain over hundreds or thousands of microns. To be able to understand the fundamental capabilities of the brain, the responses of these networks, or large parts thereof, need to be captured as completely as possible with high temporal resolution. [0003] Since this is not just about understanding morphological structures but also functional processes, these approaches are also combined under the keyword functional imaging. [0004] In the field of microscopy, many different methods are known with which functional imaging can be approximated. Method-based schemes, eg, fast 2D recording followed by axial scanning, ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G02B21/00G02B21/36G01N21/64
CPCG02B21/008G02B21/0028G02B21/365G01N21/6458G02B21/0072G02B21/18G02B21/367G02B21/0032G02B21/0052
Inventor T.安哈特D.施韦特
Owner CARL ZEISS MICROSCOPY GMBH
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