Traditional Chinese medicine dipping-soaking preparation formula for treating lower limb venous ulcer and preparation and use methods thereof

A technology for venous ulcers and traditional Chinese medicine, applied in the directions of pharmaceutical formulas, drug combinations, and medical preparations containing active ingredients, etc., can solve the problem of inability to improve the local nutritional disorder of the wound, local infection of the VLU wound, and inability to promote local granulation growth. and other problems, to achieve the effect of non-toxic side effects and allergic reactions, good clinical efficacy, and promoting the healing of sore surfaces

Active Publication Date: 2022-05-13
THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its mechanism of action is to act on ribosomes in bacteria, inhibit bacterial protein synthesis, and destroy the integrity of bacterial cell membranes; however, gentamicin has common side effects such as nephrotoxicity and ototoxicity, and patients often suffer from hearing loss, tinnitus or ear pain. Fullness (ototoxicity), hematuria, significantly decreased urination frequency or decreased urine output, loss of appetite, extreme thirst (nephrotoxicity), unsteady gait, dizziness, and even dyspnea, lethargy, extreme weakness, etc. Gentamicin is contraindicated in pregnant women
[0004] 2. At present, there are non-antibiotic antibacterial dressings on the market, including silver-containing dressings, chitosan dressings, etc. Most of them need to be used in conjunction with secondary covering dressings to form a breathable and moisturizing barrier film that can be absorbed by the body after the wound. It has a good antibacterial effect; however, although silver-containing dressings and chitosan dressings have good antibacterial effects, they cannot improve the local nutritional disorder of the wound and cannot promote the growth of local granulation
But it can't solve the local infection of VLU wound

Method used

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  • Traditional Chinese medicine dipping-soaking preparation formula for treating lower limb venous ulcer and preparation and use methods thereof
  • Traditional Chinese medicine dipping-soaking preparation formula for treating lower limb venous ulcer and preparation and use methods thereof

Examples

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Effect test

Embodiment 1

[0020] Example 1: A prescription and preparation method of traditional Chinese medicine soaked preparation for treating venous ulcer of lower extremities

[0021] Drug composition: Phellodendron 21g, Atractylodes 15g, Radix Paeoniae Rubra 15g, Angelica 12g, Rhubarb 12g, Scutellaria baicalensis 12g, Raw Astragalus 12g, Achyranthes bidentata 12g.

[0022] The preparation method is as follows: soak the medicine in distilled water for 60 minutes, add about 400-500ml of water for the first time, pour out the medicine solution, add about 300ml of water, decoct with a slow fire for 15 minutes after boiling the water, combine the two medicine solutions together, Evaporate again to 100ml, put it in a sterile bag, store it at room temperature, and avoid direct sunlight.

[0023] The clinical data of the present invention are as follows:

[0024] 1. General Information

[0025] A total of 80 patients with VLU damp-heat syndrome from November 2019 to May 2021 were selected and divided i...

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Abstract

The invention relates to a traditional Chinese medicine dipping-soaking preparation formula for treating lower limb venous ulcer and a preparation and use method thereof, and belongs to the technical field of traditional Chinese medicine preparation method application. According to the technical scheme, amur corktree bark, rhizoma atractylodis, radix paeoniae rubra, radix angelicae sinensis, radix et rhizoma rhei, radix scutellariae, radix astragali seu hedysari and radix cyathulae are taken and added into distilled water to be soaked, decoction is performed, residues are filtered out, then liquid medicine is obtained, the traditional Chinese medicine soaking preparation for treating the lower limb venous ulcer is obtained, during application, cold soaking is performed for 30 min firstly, then local fomentation treatment is performed, and dressing change is performed once every other day. The preparation and the treatment method have the advantages that the preparation can effectively promote wound healing and improve inflammatory response, and is small in side effect, short in treatment course and high in cure rate.

Description

technical field [0001] The invention relates to a prescription of a traditional Chinese medicine soaked preparation for treating venous ulcers of lower extremities and a preparation and use method thereof, belonging to the technical field of compound preparations of traditional Chinese medicines for external use. Background technique [0002] Venous leg ulcer (VLU) is a common complication of lower extremity venous insufficiency, often secondary to lower extremity deep vein thrombosis and lower extremity varicose veins, accounting for 70% of lower extremity ulcers. The clinical manifestations of the disease are skin pigmentation, dryness and desquamation, refractory sores, dripping pus, etc. in the calf and boot area. It is easy to recur and seriously affects the quality of life of the patient. The pathological mechanism of the disease is that continuous venous hypertension leads to local nutritional disorders of the wound, local chronic inflammatory response, and the format...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P9/14A61P17/02
CPCA61K36/756A61K36/284A61K36/71A61K36/65A61K36/232A61K36/708A61K36/539A61K36/481A61K36/21A61K9/0014A61P9/14A61P17/02A61K2236/331A61K2300/00Y02A50/30
Inventor 王雁南
Owner THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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