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Testing of filter device

A filter device and housing technology, applied in the direction of filter separation, measuring device, membrane filter, etc., can solve the problems of large filter size and low filter capacity

Pending Publication Date: 2022-06-03
CYTIVA SWEDEN AB
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition, low filtration capacity or absorption of specific target proteins into the filtration matrix may lead to testing a large number of different filters
Furthermore, due to the large filter sizes available and, as explained, many filters to be screened, the test required a large amount of filtered feed

Method used

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  • Testing of filter device
  • Testing of filter device
  • Testing of filter device

Examples

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Embodiment Construction

[0039] According to the present invention, there is provided a method for testing at least one filter device, wherein the method comprises using a chromatography system for testing. Screening and testing of different filter devices using already existing chromatography systems, such as depth filters, sterile filters, chromatography media or a combination of such filter types, provides a method for evaluating different filter properties effective method. Analytical components already provided in chromatography systems can be used for evaluation, such as a pressure sensor for evaluating the delta pressure on the filter device and a UV sensor for measuring the UV absorption of the sample feed flowing through the filter device. Thus, an efficient and somewhat automated testing method for filter devices is provided.

[0040] Figure 1aA system 1 for testing at least one filter device 23 according to one embodiment of the present invention is schematically shown. The system 1 incl...

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Abstract

Disclosed are systems and methods for testing at least one filtration device. The system comprises a chromatography system (3) comprising at least one pair of inlet and outlet chromatography column connections (7a, 7b) for at least one chromatography column, and at least one filter device housing (21) comprising a filter device (23) to be tested, whereby each filter device housing (21) is connected to one of the at least one pair of inlet and outlet chromatography column connections (7a, 7b), the chromatographic column is not a chromatographic column in a chromatographic system.

Description

technical field [0001] The present invention relates to systems and methods for testing at least one filter device. It also concerns the filter device housing. Background technique [0002] Filtering and testing of filters, such as depth filters, can be time-consuming. There are various filters with different properties, and so many different filters may have to be sifted through until a suitable filter is found. Additionally, low filtration capacity or uptake of the filter matrix by a specific target protein may lead to testing a large number of different filters. Furthermore, due to the large filter sizes available and, as explained, many filters need to be screened, the test requires a large amount of filter feed. SUMMARY OF THE INVENTION [0003] It is an object of the present invention to provide improved methods and systems for testing and / or screening filter devices. [0004] Another object of the present invention is to provide a more efficient method for testi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/08G01N30/02
CPCG01N15/08G01N30/02G01N2015/084G01N2015/086B01D2201/182B01D35/147
Inventor S·门泽尔
Owner CYTIVA SWEDEN AB