Method for extracting and quantifying end diastolic/mitral valve closure point from HVAD estimated flow waveform

A mitral valve and waveform technology, applied in electrocardiography, medical equipment, diagnostic recording/measurement, etc., can solve problems such as current VAD devices do not have

Pending Publication Date: 2022-07-08
HEARTWARE INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, current VAD devices do not have efficient preload tracking methods to obtain preload

Method used

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  • Method for extracting and quantifying end diastolic/mitral valve closure point from HVAD estimated flow waveform
  • Method for extracting and quantifying end diastolic/mitral valve closure point from HVAD estimated flow waveform
  • Method for extracting and quantifying end diastolic/mitral valve closure point from HVAD estimated flow waveform

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0045] Example 1. A control circuit for a sensorless implantable blood pump comprising a processing circuit configured to generate a set of estimated current and flow waveforms from the sensorless implantable blood pump at least one of; determining the mitral valve closure point from at least one estimated from the group consisting of a current waveform and a flow waveform from the sensorless implantable blood pump;

[0046] Calculate the relative index of preload;

[0047] comparing the relative index of preload to a normal baseline relative index of preload; and

[0048] The speed of the pump is adjusted based on the comparison.

example 2

[0049] Example 2. The control circuit of example 1, wherein the processing circuit is configured to pass a trough between the estimated at least one of the mitral valve closure point and the estimated at least one of the group consisting of a current waveform and a flow waveform. The preload relative index is calculated by dividing the measured amplitude between the peaks and the trough of at least one of the group consisting of a current waveform and a flow waveform.

example 3

[0050] Example 3. The control circuit of any of the preceding examples, wherein the sensorless implantable blood pump is a ventricular assist device.

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Abstract

A control circuit for a sensorless implantable blood pump configured to determine mitral valve regurgitation includes a processing circuit configured to generate an estimated blood flow waveform from the sensorless implantable blood pump and to determine the mitral valve regurgitation if between an end diastole and an initial systole. If the measured amplitude of the estimated blood flow waveform does not include an inflection point, an alert is generated.

Description

technical field [0001] The present application generally relates to a system for determining mitral valve function and cardiac preload in a patient with an implantable blood pump. Background technique [0002] Implantable blood pumps could be used to help patients with advanced heart disease. Blood pumps operate by receiving blood from and pushing blood back into the patient's vasculature. By adding momentum and pressure to a patient's blood flow, blood pumps can augment or replace the pumping action of the heart. For example, the blood pump may be configured as a ventricular assist device or "VAD". Where a VAD is used to assist the pumping action of the left ventricle, the device draws blood from the left ventricle of the heart and drains the blood into the aorta. [0003] In cardiac physiology, preload is defined as the initial stretch of cardiomyocytes prior to contraction. Sarcomere length cannot be measured directly, other preload indices such as left atrial pressur...

Claims

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Application Information

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IPC IPC(8): A61M60/178
CPCA61M60/178A61M60/216A61M60/232A61M60/422A61M60/538A61M60/546A61M2205/18A61M2230/04A61M2205/3331A61M60/148
Inventor C·雷耶斯N·L·瓦苏德万贾拉贾
Owner HEARTWARE INC
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