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Anti-malaria mosquito-repellent antibacterial composition and preparation method thereof

A composition and mosquito repelling technology, applied in the field of daily necessities, can solve the problems of increased drug resistance of mosquitoes, inability to kill or repel mosquitoes, and serious environmental hazards, so as to prevent the spread of malaria, repel mosquitoes and prevent malaria significantly, Effects of low alcohol content

Pending Publication Date: 2022-08-02
浙江澳岚丁生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Since malaria is transmitted through mosquito vectors, in traditional single-dose mosquitoicides or mosquito repellents, conventional doses of drugs cannot completely kill or repel mosquitoes
Secondly, the effect of a single dosage form of mosquitoicide or mosquito repellent gradually decreases with the time of use. If you want to achieve 100% mosquito killing or mosquito repellent effect, you need to increase the concentration of the drug or increase the frequency of medication
However, when the drug concentration and frequency of drug use increase, the toxicity to the human body and the environment will increase, the cost will increase, and the probability of drug resistance in mosquitoes will increase.
And for a long time, pyrethroid compounds have been used as the main active ingredients of mosquito killers, which have a significant effect on killing mosquitoes, but they are seriously harmful to the environment, and mosquitoes have generally developed resistance.

Method used

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  • Anti-malaria mosquito-repellent antibacterial composition and preparation method thereof
  • Anti-malaria mosquito-repellent antibacterial composition and preparation method thereof
  • Anti-malaria mosquito-repellent antibacterial composition and preparation method thereof

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Effect test

Embodiment 1

[0052] Embodiment 1, a preparation method of an anti-malarial, mosquito-repellent and bacteriostatic composition, specifically comprising the following steps:

[0053] S1. Preparation of antibacterial water:

[0054] S1.1. Weigh 1g of polyhexamethylene biguanide and add 2500ml of deionized water to make the percentage content be 0.04% (m / v) to obtain an antibacterial water mother liquor;

[0055] S2, the preparation of repellent ester antibacterial liquid:

[0056] S2.1. Take 2ml of mosquito repellent and add 200ml of lemongrass essence, mix well;

[0057] S2.2. Add 3ml of 95% ethanol and mix well;

[0058] S2.3, adding 5ml of the antibacterial jellyfish mother liquor prepared in step S1, and mixing;

[0059] S2.4, ultrasonic defoaming;

[0060] S3, the preparation of atovaquone suspension mother liquor:

[0061] S3.1. Measure 1 g of atovaquone, add 180 g of PEG-400, and mix it initially;

[0062] S3.2, add 320ml of the antibacterial jellyfish mother liquor prepared in s...

Embodiment 2

[0067]Embodiment 2, a preparation method of an anti-malarial, mosquito-repellent and bacteriostatic composition, specifically comprising the following steps:

[0068] S1. Preparation of antibacterial water:

[0069] S1.1, weigh 1g of chlorhexidine acetate and add 2000ml of deionized water to make its percentage content 0.05% (m / v), to obtain an antibacterial jellyfish mother liquor;

[0070] S2, the preparation of repellent ester antibacterial liquid:

[0071] S2.1. Take 2ml of mosquito repellent and add 1 / 200ml of lemongrass essence, mix well;

[0072] S2.2. Add 3ml of 95% ethanol and mix well;

[0073] S2.3, adding 5ml of the antibacterial water prepared in step S1, and mixing;

[0074] S2.4, ultrasonic defoaming;

[0075] (3), the preparation of atovaquone suspension mother liquor:

[0076] S3.1. Measure 1 g of atovaquone, add 100 ml of AEO-9, and mix it initially;

[0077] S3.2, add 400ml of the antibacterial water prepared in step S1;

[0078] S3.3, high-speed vacu...

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Abstract

The invention discloses an anti-malarial mosquito-repellent bacteriostatic composition and a preparation method thereof. The anti-malarial mosquito-repellent bacteriostatic composition comprises the following components: an in-vitro anti-malarial drug, a mosquito repellent, a solvent, a surfactant polyethylene glycol-400, a bacteriostatic agent polyhexamethylene biguanide, essence and deionized water. The preparation method of the anti-malaria mosquito-repelling antibacterial composition specifically comprises the following steps: preparation of antibacterial water, preparation of a mosquito-repelling ester antibacterial solution, preparation of an atorvaquone suspension mother solution and preparation of an atorvaquone mosquito-repelling ester antibacterial solution. The composition of atorvaquone and dimethyl phthalate can kill plasmodium in mosquito bodies so as to prevent malaria from spreading, and compared with an existing single mosquito repellent, the composition of atorvaquone and dimethyl phthalate has more remarkable mosquito-repelling and malaria-preventing effects; the composition is safe to human bodies, free of toxic and side effects, environmentally friendly and capable of being applied to the human bodies and the environment; the composition does not contain propellants in the formula, is low in alcohol content, and is beneficial to production, storage and transportation.

Description

technical field [0001] The invention relates to the technical field of daily necessities, in particular to an antimalarial, mosquito repellent and antibacterial composition and a preparation method thereof. Background technique [0002] Malaria is one of the parasitic diseases caused by Plasmodium that seriously endanger human health. It is mainly a syndrome caused by female mosquitoes carrying malaria parasites biting the human body and infecting the human body with the malaria parasites in the body. According to the World Health Organization's 2019 World Malaria Report, the world achieved no gains in reducing new infections between 2014 and 2018. The number of deaths from malaria in 2018 was almost the same as in the previous year. In 2018, there were an estimated 228 million cases of malaria worldwide, and about 405,000 people died of malaria worldwide. The global prevention and control of malaria still faces great challenges. Traditional chemical drugs such as chloroq...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N35/06A01N37/46A01N47/44A01P17/00A01P15/00A01P7/04
CPCA01N35/06A01N37/46A01N47/44
Inventor 董青青黄文超
Owner 浙江澳岚丁生物科技有限公司
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