Application of licorcidine in preparation of medicine or food for treating obesity and complications thereof

A technology of licorice and comorbidities, applied in the field of medicine, can solve the problems of decline, even malignant vomiting, poor digestion and absorption of food, unsatisfactory weight loss effect, etc., achieves a good development prospect, increases the energy consumption of the body, and does not affect the central nervous system. Nervous system effects

Pending Publication Date: 2022-08-05
THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

Drugs that reduce food intake mainly act on GLP-1 receptors in the gastrointestinal tract and nerve center, leading to increased satiety and decreased appetite, which usually cause discomfort such as abdominal fullness, decreased concentration, and even malignant vomiting. In addition, it is often affected by the patient's living and eating habits, which leads to dissatisfaction with the weight loss effect.
Weight-loss drugs that reduce absorption mainly inhibit digestive enzymes and cause poor digestion and absorption of food. At present, this drug is currently limited in clinical application because of side effects such as abdominal pain and severe diarrhea.

Method used

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  • Application of licorcidine in preparation of medicine or food for treating obesity and complications thereof
  • Application of licorcidine in preparation of medicine or food for treating obesity and complications thereof
  • Application of licorcidine in preparation of medicine or food for treating obesity and complications thereof

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Embodiment Construction

[0045] In order to make those skilled in the art better understand the technical solutions in the present application, the technical solutions in the embodiments of the present application will be described clearly and completely below. Obviously, the described embodiments are only a part of the embodiments of the present application. , not all examples. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present application.

[0046]All animal models in this experiment were established on C57BL / 6 wild-type mice, and the mice were ordered from Hunan Slike Jingda Laboratory Animal Co., Ltd. All mice were kept in a specific pathogen free (SPF) barrier animal laboratory, the indoor temperature was kept at 24°C, and the daily light and dark time were maintained for 12 hours each (ie, light time: 6:00 -18:00; dark hours: 18:00-6:00).

[0047...

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Abstract

The invention discloses application of licorcidine in preparation of a medicine or food for treating obesity and complications thereof. The invention provides application of licocidin in preparation of medicines or foods for treating obesity and complications thereof, and the licocidin can be used for effectively treating obesity and complications thereof through a brand-new action mechanism, namely induction of beige of white fat, promotion of heat production of fat and increase of energy consumption of an organism.

Description

technical field [0001] The present application relates to the technical field of medicine, in particular to the use of licorice in the preparation of medicines or foods for the treatment of obesity and its complications. Background technique [0002] Obesity is caused by the imbalance between the body's energy intake and expenditure. If the long-term energy intake exceeds energy expenditure, the excess energy will be stored in the form of fat, which will cause the increase of adipose tissue, which will lead to obesity and obesity-related comorbidities in the long run. Obesity is currently on a global scale. According to WHO data, the number of obese people in the United States and Western countries nearly tripled between 1975 and 2016. Data show that in 2016, about 1.9 billion people were overweight and 650 million were obese, with overweight and obesity accounting for 39% and 13% of the global population, respectively. At the current rate of progress, 51% of adults worldw...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A23L33/10A61P3/04
CPCA61K31/352A61P3/04A23L33/10A23V2002/00A23V2200/332A23V2250/2116
Inventor 刘威刘峰孟文金章留
Owner THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV
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