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IDE interdigital electrode manufacturing and pre-functionalization processing method

A processing method and interdigital electrode technology, which is applied in the field of IDE interdigital electrode production and pre-functionalization treatment, can solve the problems of affecting electrical signals, complicated manufacturing, and limitation, and achieve the effect of improving sensitivity

Pending Publication Date: 2022-08-05
CHANGZHOU TRENDI MEDICAL TECH CO LTD
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  • Abstract
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Problems solved by technology

However, most biosensors require specific redox agents or labels to generate signals, and are limited to specific electrode designs, which are complex to manufacture and require high-end instruments for signal measurement.
In addition, some sensors form sulfur-gold bonds on the gold and then immobilize the required biological probes, resulting in high cost, and the redox agents in the impurities are also easy to affect the electrical signal.

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  • IDE interdigital electrode manufacturing and pre-functionalization processing method
  • IDE interdigital electrode manufacturing and pre-functionalization processing method
  • IDE interdigital electrode manufacturing and pre-functionalization processing method

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Embodiment Construction

[0050] In order to make the objectives, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be described in detail below. Obviously, the described embodiments are only some, but not all, embodiments of the present invention. Based on the embodiments of the present invention, all other implementations obtained by those of ordinary skill in the art without creative work fall within the protection scope of the present invention.

[0051] The purpose of the present invention is to provide a method for fabricating and pre-functionalizing an IDE interdigital electrode. The above method includes using micro-nano processing technology to fabricate an interdigital electrode (IDE) structure with a spacing of only a few microns in a clean room, and successfully immobilizing the oligonucleotide probe sequence complementary to the target gene through a series of chemical reactions. On the electrodes, pre-functionalizat...

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Abstract

According to the manufacturing and pre-functionalization processing method of the IDE interdigital electrode, a high-precision micro IDE sensor and a high-precision biosensor are combined through a micro-nano processing technology, and the sensitivity of subsequent detection is improved. Since the binding position with the probe in the functionalization step is not on a conventional electrode, a specific redox agent / label is not required to generate a signal for detecting the target. In addition, the designed and manufactured IDE sensor type can be easily optimized and used according to detection targets, attention to use items, and user electronic requirements.

Description

technical field [0001] The invention relates to the technical field of IDE biosensors, in particular to a method for manufacturing and pre-functionalizing an IDE interdigital electrode. Background technique [0002] Interdigitated electrodes (IDE) refer to microelectrodes deposited on a substrate, the working and counter electrodes exhibiting the appearance of interdigitated fingers or patterns with small spacing that recur periodically. Interdigital electrodes are generally used in microwave filters, surface acoustic wave devices, electro-optic shutters, but also in materials with electrical and dielectric properties, such as affinity biosensors, including label-free (direct / redox-free) and Labeled (redox) biosensors. [0003] A number of methods have been developed for the detection of pathogens, viruses, isothermal amplification and PCR amplification products. Among them, the application of biosensors has been widely reported. However, most biosensors require specific ...

Claims

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Application Information

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IPC IPC(8): G01N27/327
CPCG01N27/327
Inventor 关国良阿桑卡陈建雄陈薛名金诚陈巧玲
Owner CHANGZHOU TRENDI MEDICAL TECH CO LTD