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Biological medicine film and its preparation method

A technology of biological medicine and traditional Chinese medicine, which is applied in pharmaceutical formulations, medical raw materials derived from arthropods, and medical preparations containing active ingredients, etc., can solve the problems of accelerating healing speed, shortening treatment time, slow healing speed, etc. Ability, increase healing ability, promote repair effect

Inactive Publication Date: 2003-04-23
北京中科天鹤生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The purpose of the present invention is to overcome the shortcomings of the prior art such as slow healing speed, poor curative effect, no peculiar smell, and strong pain during treatment, and provide a brand-new biomedical film, which can accelerate the healing speed and shorten the treatment time. And can relieve the pain during the treatment, at the same time no smell, no obvious foreign body sensation

Method used

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  • Biological medicine film and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1: the preparation of biopharmaceutical film

[0050] 1. Preparation of traditional Chinese medicine suspension: put 500g of housefly larvae in a grinder, add an appropriate amount of distilled water and grind, then centrifuge the grinding solution at 4°C and 15000r / min for 30 minutes, and take the supernatant as blood A mixture of lymph and water. Then gallnut 180g and borneol 60g were ground into powder, passed through 120 mesh, added to the mixture of hemolymph and water, then added appropriate amount of water and a small amount of starch, stirred evenly to make 1000ml of suspension with a concentration of about 26%.

[0051] 2. Preparation of chitosan glue: Dissolve 40g chitosan in 2000ml, 1% dilute hydrochloric acid solution, stir at room temperature until completely dissolved, let stand to remove insoluble matter, and prepare chitosan glue with a concentration of 2%. spare.

[0052] 3. Preparation of gelatin paste: add appropriate amount of water to 2...

Embodiment 2

[0056] Embodiment 2: the preparation of biopharmaceutical film

[0057] 1. Induction of housefly larvae: remove 1 plate of maggot culture plate grown to 3 instars from the breeding room, and treat it with hot air at 50°C for 30 minutes in the induction treatment room, and then separate the induced maggots from the feed with a separator. The separated 1kg fly maggots were placed on a homemade pin shaker and vibrated for 30 minutes, then cultivated at a temperature of 25° C. and a humidity of 70% for 24 to 48 hours until about 30% of the larvae pupated.

[0058] 2. Preparation of traditional Chinese medicine suspension: put the above-mentioned 1kg housefly larvae in a grinder, add an appropriate amount of distilled water and grind, then centrifuge the grinding solution at 4°C and 15000r / min for 30 minutes, and take the supernatant as A mixture of hemolymph and water. Then grind 450g gallnut and 180g borneol into powder, pass through 120 meshes, add into the mixture of hemolymph...

Embodiment 3

[0064] Example 3: Preliminary clinical test of biological drug film.

[0065] 1. Experimental objects: 76 patients with oral ulcers were randomly selected as observation objects. Among them, there were 40 males and 36 females, aged from 10 to 56 years, with an average of (37±4) years old, with a duration of 1d to 2 years, with an average of (1±0.8) months.

[0066] 2. Usage

[0067] Instruct the patient to rinse his mouth with warm boiled water first, and then put the medicine film on the ulcer wound, and the continuous medicine should not exceed 4 days.

[0068] 3. Judgment of curative effect

[0069] Significantly effective: after treatment, the pain and redness decreased or disappeared, and the ulcer healed within 2 days, and the healing time was significantly shorter than before; effective: after treatment, the pain and redness were relieved, but the ingestion of irritating food still felt uncomfortable, and the ulcer healed within 4 days Internal healing; invalid: the pa...

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Abstract

The preparation method of biological medicinal membrane for curing stomatocace includes the following steps: preparing Chinese medicine suspension, it is made up by using Chinese medicinal materials of borneol, larva of common house-fly and suma gallnut; preparing chitosan colloidal pulp; preparing gelatin colloidal pulp; preparing membrane colloidal pulp; forming medicinal membrane; sterilizing and packaging. Its composition is formed from (by weight portion) 35-45 portions of chitosan colloidal pumlp, 5-15 portions of gelatin colloidal pulp and 20-30 portions of Chinese medicine suspension.

Description

technical field [0001] The invention belongs to the branch of medical dressings in the field of medicine, relates to a biomedical film obtained by utilizing biotechnology and a preparation method thereof, in particular to a method which utilizes chitosan and gelatin as substrates, and is compatible with borneol, housefly larvae, A biomedical film prepared from traditional Chinese medicines such as gallnut (stir-fried) and a preparation method thereof. Background technique [0002] With the rapid development of modern science and technology, the research on medical dressings has made very fast progress. Various new types of medical dressings continue to appear, and their performance is getting better and better. New dressings, also known as active dressings or revolutionary dressings, generally refer to those types of dressings that are different from traditional dressings (gauze) in appearance, and can actively participate in and affect the speed and...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K35/64A61K47/36
Inventor 张廷军韩晓琨
Owner 北京中科天鹤生物技术有限公司
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