Use of CD 23 antagonists for treatment of neoplastic disorders

An antagonist, tumor technology, applied in the direction of diseases, anti-tumor drugs, skin diseases, etc., can solve the problem of unsustainable remission
CN1494433AInactive Publication Date: 2004-05-05IDEC PHARM CORP
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
IDEC PHARM CORP
Publication Date
2004-05-05
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention provides methods and kits for treating neoplastic diseases, including the use of CD23 antagonists. The CD23 antagonists can be used alone or in combination with chemotherapeutic agents. In a particularly preferred embodiment, the CD23 antagonist may be used in the treatment of B-cell chronic lymphocytic leukemia (B-CLL).
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Description

[0001] Cross References to Related Applications

[0002] This application claims priority to the following patent applications: U.S. Serial No. 09 / 772,938, filed January 31, 2001; U.S. Serial No. 09 / 855,717, filed May 16, 2001; and U.S. Serial No. 09 / 985,646, filed on , each of which is incorporated herein by reference in its entirety. field of invention

[0003] In a broader aspect, the invention relates to the use of CD23 antagonists for the treatment of neoplastic diseases. In a preferred embodiment, the present invention provides the use of an anti-CD23 antibody for immunotherapy of malignancies, including B-cell chronic lymphocytic leukemia (B-CLL). Background of the invention

[0004] Patients with a wide variety of malignancies have benefited from advances in cancer treatment over the past few decades. Unfortunately, most patients eventually succumb to their disease despite modern therapies that greatly increase regression rates and prolong survival. Barriers to be...

Claims

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