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Method of non destructive measuring biological active tissue heat parameter

A living tissue, biological tissue technology, applied in diagnostic recording/measurement, medical science, sensors, etc., can solve problems such as inconvenience of use and operation

Inactive Publication Date: 2004-12-22
UNIV OF SCI & TECH BEIJING
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This probe is good for thermal measurements, but not easy to use and handle

Method used

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  • Method of non destructive measuring biological active tissue heat parameter

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Embodiment Construction

[0022] In a specific implementation, it is assumed that within the measured temperature range, the columnar living tissue is isotropic and its thermal parameters are constant, and it is considered that the heat of blood flowing through the cross section of the columnar living body is balanced. Under the established cylindrical coordinates, in the two-dimensional Pennes heat transfer model of the columnar biological living tissue with length L = 0.32m and radius R = 0.045m, the governing equation and boundary conditions are shown in Equation 4 and Equation 5 respectively:

[0023] ( ρc ) t ∂ T ∂ t = k [ ∂ 2 T ∂ x 2 ...

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Abstract

A nondestructive method for measuring the thermal parameters of the tissue of living things by measuring the temp of three points on surface includes creating 2D heat-transfer. Pennes model of cylindrical living tissue in histogram coordinate system, using line-by-line method to find out the temp variation of living tissue under interference of step heat flow or square-wave heat flow, calculating its sensitivity, analyzing the correlation between the sensitivity coefficients of thermal parameters and the influence of thermal parameters to temp variation, optimizing the selection of three measured points, developing its measuring system, and using Gauss estimating method to obtain various thermal parameters.

Description

technical field [0001] The invention belongs to the technical field of biological living body measurement, and in particular provides a method for non-destructively measuring thermal parameters of biological living tissue, which determines the thermal conductivity, thermal diffusivity, blood perfusion rate and volumetric heat capacity of columnar biological living tissue through three-point surface temperature measurement Method for isothermal parameters. Background technique [0002] The measurement of thermal parameters of biological living tissue is the key to in-depth study of the heat transfer characteristics and mechanism of organisms and the reconstruction of tissue temperature field. However, the anisotropy of biological materials, large differences between different samples of the same type, thermal properties of tissues under various physiological states, and changes in blood perfusion rate and metabolic heat production all pose many difficulties for the measuremen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B5/01
Inventor 张欣欣乐恺于帆姜泽毅冯研卉林林
Owner UNIV OF SCI & TECH BEIJING
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