Optical waveguide biochemical sensor and measurement system based on free space coupling

Abstract

It is a light wave-guide biochemistry sensor and its measurement system based on free space couple, which belongs to accuracy analysis and measurement device. The light wave guide biochemistry sensor is fixed on the center of the upper disc of the optics rotation desk, which comprises upper metal film, upper optics glass sheet, solvent chamber, ground optics glass sheet, ground metal film, cushion block, platform and micrometer screw gage. The upper metal film deposits on the upper optics glass sheet and the ground metal film deposits on the ground optics glass sheet. The metal film surface of upper optics glass sheet faces upward and that of the ground optics glass sheet faces downward. The upper optics glass sheet, solvent chamber, ground glass sheet are orderly folded and laid on the platform with cushion block supported, which are tightly supported through micrometer screw gage.

Description

technical field [0001] The invention relates to a sensor and a measurement system composed of the sensor, in particular to a free-space coupling-based optical waveguide biochemical sensor without a prism coupling unit and a measurement system. It is used in the field of precision analysis and measuring instruments. Background technique [0002] Since the late 1980s, sensors based on surface plasmon resonance (SPR), optical waveguide, and fiber optic technologies have received extensive attention. This type of sensor is simple in structure, easy to use, and reliable, and can be applied to the measurement of multiple parameters in the fields of biology, chemistry, and physics, especially in the fields of protein structure, antibody antigen detection, and other important applications. A common feature of this type of sensors is that the sample to be measured is in the evanescent field region of the resonant mode (surface plasmon wave and optical guided wave). Therefore, such ...

AI Technical Summary

Problems solved by technology

Disadvantages: (1) For sensors based on leaky optical waveguide and optical fiber technology, the width of the resonant mode ATR absorption peak may be very narrow, but its samples are usually used as the cladding layer of optical waveguide or optical fiber, and the light in the cladding layer can account for only a few percent of the total light energy of the resonant mode

Therefore, the sensitivity of evanescent field sensors based on leaky optical waveguide and fiber optic technology cannot usually be made very high

(2) For the SPR sensor, although more than half of the light energy is in the detection area, it has a high detection efficiency, but due to the absorption of the metal film, the width of the ATR absorption peak is very large, and it is also difficult to achieve a large High detection sensitivity

However, the sensor uses coupling devices such as prisms, which greatly restricts the above method in the measurement field that requires a small device size, and at the same time has certain difficulties in realizing small-angle detection

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