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Bacteria and virus resisting and inflammation eliminating eye drop and its preparing process

A technology of anti-inflammatory effect and eye drops, which is applied in the field of eye drops, can solve problems such as unsatisfactory results and no eye drops found

Inactive Publication Date: 2005-06-29
吴梅春
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, although the Houttuynia eye drops made from the volatile oil of a single part extracted from a single medicinal Houttuynia cordata has achieved certain therapeutic effects in the treatment of ophthalmic diseases, the results are not satisfactory.
[0008] No reports of eye drops made from forsythia and houttuynia were found in the data retrieval

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0246] Grind 100g of forsythia and 120g of Houttuynia cordata, add 12 times the amount of water to soak for 2 hours, extract by steam distillation for 4 hours, collect the volatile oil, keep the water extract and medicinal residues; add 10 times the amount of water to decoct the medicinal residues for 2 hours hours, combined two water extracts, filtered, the filtrate was concentrated under reduced pressure to a solution: medicinal materials were 1: 1.5, added ethanol until the alcohol content reached 85%, stood for 36 hours, filtered, and the filtrate was reclaimed at 60°C for ethanol and concentrated To the clear paste with a relative density of 1.25, dry the clear paste at 70°C and 6.6Kpa under reduced pressure to obtain the extract; heat and dissolve the extract with a phosphate buffer solution with a pH value of 7.38, and filter to obtain an extract solution; Mix the volatile oil of forsythia and houttuynia cordata with 8ml Tween-80, stir and add to the above extract soluti...

Embodiment 2

[0248] Crush 60g of forsythia and 80g of Houttuynia cordata, add 6 times the amount of water to soak for 0.5 hours, extract by steam distillation for 2 hours, collect volatile oil, water extract and medicinal residues for use; add 6 times the amount of medicinal residues to decoct for 0.5 hours , combined two water extracts, filtered, and the filtrate was concentrated under reduced pressure to a solution: the medicinal material was 1:1.5, and ethanol was added until the alcohol content reached 60%, left to stand for 12 hours, filtered, and the filtrate was reclaimed at 60°C for ethanol and concentrated to For the clear paste with a relative density of 1.28, dry the clear paste at 70°C and 6.6Kpa under reduced pressure to obtain the extract; heat and dissolve the extract with a phosphate buffer solution with a pH value of 7.38, and filter to obtain an extract solution; Forsythia, Houttuynia volatile oil mixed with 3ml Tween-80, stirred and added to the above extract solution, th...

Embodiment 3

[0250] Crush 80g of forsythia and 100g of Houttuynia cordata, soak in 10 times the amount of water for 1 hour, extract by steam distillation for 3 hours, collect the volatile oil, keep the water extract and medicinal residues for use; add 8 times the amount of water to decoct the medicinal residues for 1 hours, combined two water extracts, filtered, the filtrate was concentrated under reduced pressure to a solution: medicinal materials were 1:1.5, added ethanol until the alcohol content reached 70%, stood for 24 hours, filtered, and the filtrate recovered ethanol and concentrated at 60°C To the clear paste with a relative density of 1.26, dry the clear paste at 70°C and 6.6Kpa under reduced pressure to obtain the extract; heat and dissolve the extract with a phosphate buffer solution with a pH value of 7.38, and filter to obtain an extract solution; Mix the volatile oil of forsythia and houttuynia cordata with 5ml Tween-80, stir and add to the above extract solution, then add 4...

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Abstract

Disclosed is an eye drop with functions of antibiotic, antiviral and anti-inflammatory, which is prepared from capsule of weeping forsythia, houttuynia cordata extract, and solubilizing agent, osmoregulation agent, anti-oxidant agent, viscosity increaser, and preservative agent. The invention also discloses the process for preparing the eye drop. Pharmacological experiment shows that, the eye drop can be used for effectively treating ophthalmological diseases.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and specifically relates to an antibacterial, antiviral and anti-inflammation eye drop and a preparation method thereof. The eye drop is also called Yanchaoshu eye drop. Background technique [0002] Ophthalmic diseases caused by viruses and bacteria are often accompanied by inflammation, which seriously damages the patient's vision, and often occurs repeatedly, interfering with the normal work and study of the patient, and seriously affecting the physical and mental health of the patient. Among ophthalmic diseases, herpes simplex keratitis (HSK) caused by herpes simplex virus type 1 (HSV-1) infection is the most prevalent. The onset and recurrence of HSK are related to the direct infection of the virus and the disorder of the body's immune response and immune regulation. [0003] Clinical treatment of ophthalmic diseases usually adopts oral, injection and topical a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61P27/02
Inventor 吴梅春
Owner 吴梅春
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