52 results about "Osmoregulation" patented technology

The invention relates to a water circulation system and a method for breeding marine fishes inland, and mainly solves the technical problems of complex process, large investment, high operating cost, large limitation of breeding varieties, low survival rate, slow growth and the like in the process of breeding the marine fishes in fresh water or low salinity salt water at present. A technical scheme comprises the following steps of: a, establishing the water circulation system; b, performing domestication on juvenile fishes of the marine fishes in the low salinity salt water in a gradient mode, namely breeding the juvenile fishes which are bred in the seawater in the brackish water temporarily, formulating a domestication strategy of slowing salinity gradually, and performing domesticationon the juvenile fishes of the marine fishes through three gradients, namely the brackish water phase, the low salinity phase and the ultra-low salinity phase; c, adding a physiological salt preparation, namely adding metal ions which play a key role in osmoregulation into the water or a feed; and d, managing the breeding, namely providing a preference temperature, illumination intensity and a daily illumination period. The water circulation system and the method are mainly used for breeding the marine fishes inland.

The invention relates to a vinorelbine emulsion which comprises (by weight ratio) vinorelbine 0.001-10%, emulsifying agent 0.1-20%, triglyceride compounds 0.1-30%, osmoregulation agent 0.1-10%, stabilizing agent 0.05-5%, anti-oxidant 0.01-5%, and balancing water for injection. The invention has the advantages of increased medicament stability and improved curative effect.

Disclosed is a hemostatic injection of carbazochrome sodium sulfonate and method for preparation, wherein the injection comprises carbazochrome sodium sulfonate 0.005-0.5 wt%, the optimum content being 0.008-0.2%, auxiliary solvent 0.001-0.5 wt%, the optimum content being 0.002-0.1%, osmoregulation agent 0.8-15 wt%, and water for injection 84.0-99.1%. The preparing process consists of boiling, filtering, removing charcoal, adjusting pH to 4.5-6.5, passing soup through a charcoal layer, loading into transfusion bottles, venting nitrogen, rolling the caps, and sterilizing.

The invention relates to a pharmaceutical composition containing silybin or its salts as the active constituents, the composition also comprises water-soluble bulking agent, pH regulator, stabilizer, water for injection, and osmoregulation agent. The pH of the disclosed freeze-dried powder injection, injection and transfusion is between 7-9 under aqueous solution state, the stabilizing agent is preferably tris(hydroxymethylamino)methane. The pharmaceutical composition can be used for treating acute hepatitis.

The invention relates to an eye microemulsion and process for preparation, wherein the microemulsion is prepared from oil phase, emulsifying agent, adhesion promoter, osmoregulation agent, bacteria inhibitor, sodium hydroxide and purified water through the steps of shearing and high pressure homogenizing, wherein non-ionic surface active agents such as polyoxyethylene, castor oil or polyoxyethylene hydrogenated castor oil is used as the emulsifying agent, and the auxiliary materials also include glycerin, castor oil or GTCC.

The invention discloses a chloramphenicol eye ophthalmic gel and a preparation method thereof; every 1000ml of the chloramphenicol eye ophthalmic gel contains 5-50g of chloramphenicol, 0.05-1g of preservative, 1.0-7.5g of osmoregulation agent, 30-150g of gel stroma, and rest amount of acid-base buffering agent and water used for injection. Due to the optimization and technique improvement of the auxiliary materials, the medicine dosage forms of the chloramphenicol are enriched, detention time of the medicine in the eyes are greatly prolonged, and the medicine can exert the drug effect, thus not only improving healing efficacy, but also reducing the times and days for taking medicine, decreasing the part side effect of the medicine and the untoward effect caused by the whole body absorption, as well as having no pessimal stimulation response.

The invention discloses a brimonidine tartrate eye drops ophthalmic gel and a preparation method thereof; every 1000ml of brimonidine tartrate eye drops ophthalmic gel contains 1-4g of brimonidine tartrate eye drops, 0.05g of preservative, 1.0-7.5g of osmoregulation agent, 30-150g of gel stroma, and rest amount of acid-base buffering agent and water used for injection. Due to the optimization and technique improvement of the auxiliary materials, the medicine dosage forms of the brimonidine tartrate eye drops are enriched, detention time of the medicine in the eyes are greatly prolonged, the healing effect is improved, and no pessimal stimulation response exists.

The invention discloses novel application for Ectoine, namely application of the Ectoine in preparing medicines of treating arthritis. The effective dosage range of the Ectoine is 0.1 to 100 mg/kg of body weight, preferably 8 to 50mg/kg of the body weight. When in use, the Ectoine can be used independently, or can be combined with other medicines for use. The Ectoine has high water solubility and osmoregulation function; and the experiment proves that the Ectoine can stabilize joint tissue and joint synovia, improve the adaptability of the joint tissue to environment change and improve the curative effect of other components in a preparation except for the Ectoine, so the Ectoine can be used for treating the arthritis.

The invention provides an osmoregulation initiation method of sorghum seeds under saline-alkali stress. The osmoregulation initiation method comprises the following steps of: preparing initiating agents a and b of the seeds; in a cleaning ware, filling warm water with the temperature of 55-57 DEG C and setting the water amount to be 5 times of the volume of the seeds, immersing the seeds into the warm water, continuously stirring, stopping stirring when the water temperature falls to 30 DEG C, and filtering water; diluting the initiating agent a and b of the seeds by 500 times, pouring the initiating agent a of the seeds into the ware, soaking for 30 minutes, then pouring the initiating agent b of the seeds, stirring, soaking for 16-20 hours, wherein the amounts of the initiating agents a and b of the seeds are same and are twice of the volume of the seeds and the temperature is set to be 25-28 DEG C; and filtering the seeds, bleaching for once to twice with clean water, absorbing the moisture, putting the seeds into a special oven for back drying, setting the temperature to be 40 DEG C, controlling the water content in back drying to be 8.0%+/-0.2%, and sowing or storing the seeds immediately.

The invention discloses a kandelia candel (L.) druce ERF (ethylene-responsive element binding factor) transcription factor as well as an encoding gene, an expression vector and application thereof. In the invention, the nucleic acid sequence of the ERF transcription factor cDNA separated from mangrove plant kandelia candel (L.) druce is as shown in SEQ ID No.1. After the ERF transcription factor cDNA is transformed to tobacco, the contents of osmoregulation substances (such as proline) of a transgenic plant are obviously increased, and the salt tolerance of the transgenic plant is obviously improved. An experimental result indicates that the ERF transcription factor can response an adverse signal, thereby effectively improving environmental stress resistances of the plant such as salt andbase resistance, diseases and pets resistance and the like.

The invention is concerned with the method of preparation for the 1000ml. instant taurine ophthalmic gelatin. It contents: taurine 5-50g, antiseptic 0.05-1g, osmoregulation 1.0-7.5g, gel substrate 30-150g, and the certain amount of acid-base buffer and injection usage water to fulfill the requested weight of the medicine. The invention enriches the pharmaceutical dosage form of the taurine that prolongs the residence time of the medicine at the eye areas, and improves the curative effect with no negative stimulation.

The invention discloses a method and an apparatus for automatic control watering. The method comprises the steps of burying an container that has a reverse osmosis membrane thereon and liquid that has osmoregulation substance therein in an area that needs watering; part of the reverse osmosis membrane on the container is in full contact with the soil of the area that needs watering; the expansion force or contraction force generated in the container due to the change of the water potential of the soil in the watering area is used to open and close a water-supply-pipe connected to a water source. According to the invention, the watering can be controlled without relying on outside energy; the watering can be controlled according to the soil water potential, therefore the purpose of watering based on demand is realized; water content supply for plant growth can be completely satisfied; the rotten root caused by over watering is avoided; and the water can be saved.

Absorbent products and wet wipes are disclosed that are useful in reducing the amount of ammonia produced by bacteria on or near the skin or in bodily fluids such as urine. The products described herein contain an osmoregulation protector which when introduced into a bacteria-containing environment interacts with the bacteria and reduces the amount of ammonia produced by the bacteria without significantly affecting the growth rate of the bacteria. The osmoregulation protectors described herein are particularly useful in combination with adult incontinence garments where the control of odors from bacterial by-products such as ammonia is highly desirable.

The invention relates to a Vitexin injection or oral administration preparation for treating cardiovascular diseases and process for preparation, wherein each 1000ml of the Vitexin injection comprises Vitexin 0.1-100g, each 1000 dosage units of the oral administration preparation comprises Vitexin 0.1-100g, and medicinal supplementary materials comprises diluent, flow aid, auxiliary solvent, excipient and osmoregulation agent.

The invention relates to a controlled release formulation for constant speed releasing Nitrendipine, wherein the medicament is released at a constant speed, and the blood medicament concentration waves smoothly. The release sheet is a single-chamber infiltration pump comprising the two portions of a powder core containing Nitrendipine and preparation formed by semipermeable membrane with minipores and having permeability only for small molecules such as that of water (mg/part), Nitrendipine 10-50, osmoregulation agent 3-80, propelling agent 1-50, bonding agent 1-20, right amount of lubricating agent, while the semipermeable membrane comprises semi-permeable membrane material 1-50 and aperture making agent 1-50. The invention can realize constant speed release, thus achieving the goal of smooth hypertension.

The invention discloses cornea protecting composition as well as a preparation method and an application thereof. Main components of the composition comprise a solid moisturizing and lubricating component, a liquid moisturizing and lubricating component, an osmoregulation component and water. The composition adopts double moisturizing and lubricating components including the solid moisturizing and lubricating component and the liquid moisturizing and lubricating component, so that the composition can be better spread and remained on the corneal surface and better protect the corneal epithelial layer, and damage caused by dryness to the cornea can be avoided. For a preparation process of the composition, a solution is not required to be heated to boiling, preparation operation is simpler, a preparation cycle is shorter than 48 h, cold storage is not needed during transportation and storage, and the transportation cost and use cost are reduced.

The invention relates to an eye gel or in-situ gel and preparation method, comprising base compositions and auxiliary materials, wherein the base compositions include pearl powder extract, borneo camphor, tinkalite, boric acid, ethanol, gel base and glycerine, the auxiliary materials include osmoregulation agent and bacteriostatic agent.

The invention relates to the technical field of after-harvest preservation of citrus and particularly relates to an after-harvest plant preservative containing a silktree albizia bark extract and usedfor citrus. The preservative comprises the following components: 6.25-50 parts of the silktree albizia bark extract, 0.5-2.0 parts of a film former, 0.5-1.0 part of a cosolvent, 0.5-1.5 parts of a preservative, 0.5-1.0 part of a pH value regulating reagent, 0.5-2.0 parts of an osmoregulation agent, 0.5-3.0 parts of an antioxidant and 1000 parts of water. The novel after-harvest preservative for citrus is prepared by taking the natural Chinese herbal medicine silktree albizia bark extract as the main effective component, the advantage of obvious bacteriostatic effects of the silktree albizia bark extract is fully utilized, and other auxiliary components are reasonably and scientifically blended, so the preservative has the characteristics of good preservation effects, no chemical residue,no health hazard to a human body, no pollution to the environment and the like and has good application values.

An aqueous, sterile pharmaceutical composition suitable for parenteral administration for the treatment of cardiac conditions, comprising methyl-3-[4-(2-hydroxy-3-isopropylamino)propoxy] phenylpropionate hydrochloride (esmolol hydrochloride), a buffering agent and an osmotic-adjusting agent, as well as a method for its manufacture, are disclosed.

The invention relates to a stable solution containing tiopronin for injection which comprises tiopronin and anti-oxidant as anti-oxidant, wherein the chelating agent is calcium disodium edeate, the acidity regulator is natrium hydroxydatum, osmoregulation agent is sodium chloride, and the bacteria inhibitor is benzoic alcohol. The invention can effectively guarantee the constancy of t he injections during storage and application. The product employs a dosage form of transfusion, thus is especially suitable for in-hospital treatment and patients with difficulty in deglutition.

Disclosed is an eye drop with functions of antibiotic, antiviral and anti-inflammatory, which is prepared from capsule of weeping forsythia, houttuynia cordata extract, and solubilizing agent, osmoregulation agent, anti-oxidant agent, viscosity increaser, and preservative agent. The invention also discloses the process for preparing the eye drop. Pharmacological experiment shows that, the eye drop can be used for effectively treating ophthalmological diseases.

The invention relates to a vitamin B12 collunarium liquid preparation, which is prepared from vitamin B12, adhesion promoter, pH modifier, osmoregulation agent and preservative agent.

The invention relates to nm compounding eye drip that contains peptide drug and the manufacture method. It adopts beta-carotene covering calcium phosphate nm particle as carrier to transmit peptide drug. The eye drip includes calcium phosphate nm particle, beta-carotene, peptide drug, distilled water, suitable osmoregulation agent, antiseptic and the pH value is between 6.5 and 7.5. The method includes: making calcium phosphate nm particle, covering beta-carotene over calcium phosphate nm particle, compounding eye drip with peptide drug. The advantages of the invention are that it changes the administrating method of the peptide drug; reducing the risk and side-effect; improving drug chroma in aqueous humor, etc.

The invention discloses a composition for relieving mycteroxerosis. The composition is prepared from a lubricant, a humectant, an osmotic regulating agent, a microcirculation improver and a skin restoration agent; the composition is specifically prepared from the following components in parts by weight in every 100 parts: 5 to 20 parts of a lubricant, 0.1 to 0.25 part of a humectant, 10 to 15 parts of an osmotic regulating agent, 0.1 part of a microcirculation improver, 0.1 to 0.5 part of a skin restoration agent and the balance of distilled water. The composition disclosed by the invention can fully exert the excellent lubricating and moisturizing functions, and benefit the nasal ventilation while maintaining appropriate humidity of a nasal environment; meanwhile, the microcirculation improver and the skin restoration agent can improve minor wound caused by dryness, keep nasal mucosa complete and healthy and improve various nasal problems. The composition disclosed by the invention has the advantages of safe components, high practicality, scientific prescription ratio and easiness in popularization.

The present invention provides a dry eye symptom moisturizing spray. The moisturizing spray mainly comprises a water-supplementing and moisturizing ingredient, an inflammation inhibitor, an ulcer repairing component, an osmotic adjusting agent and a pH buffering agent. Every 100 parts by weight of the moisturizing spray comprises the following components in parts by weight: 0.01 part-0.1 part of the water-supplementing and moisturizing ingredient, 0.1 part-0.3 part of the inflammation inhibitor, 0.15 part-0.3 part of the ulcer repairing component, 0.6 part-0.9 part of the osmotic adjusting agent and the balance ultrapure water, and the pH buffering agent is used to adjust pH value into 7.0-7.5. The present invention also provides a preparation method of the moisturizing spray. The moisturizing spray is specially used for relieving and treating related symptoms of dry eye syndromes, a special atomized moisturizing device generates micron-sized atomized droplets to warm and moist eyeballparts, wherein the water-supplementing and moisturizing component can maintain moisture for a long time and relieve the dry eye syndromes of eyeballs, and the dry eye symptom moisturizing spray is safe and non-toxic in ingredients, low in irritation and relatively high in user compliance.

The invention discloses a method for adopting lanthanum to enhance the acid rain resistance of garbage compost matrix Festuca elata turf. The method comprises the following steps of: adding 60g of garbage compost into a plastic cup; selecting full Festuca elata seeds; weighing 0.5g of the Festuca elata seeds and sowing in the cup; culturing in a laboratory at room temperature; 17 days later, applying the rare earth lanthanum with a concentration of 0.2-0.4g.kg<-1> and continuously culturing for 10 days, wherein the temperature of the laboratory in the culturing period is 23-30 DEG C and the relative humidity is 35-70%; starting to spray acid rain, wherein 12ml of acid rain is sprayed one time, the acid rain is sprayed one time per 5 days and the acid rain is totally sprayed 5 times; and measuring all indexes after treating. A test result of the method provided by the invention shows that under a condition of acid rain stress, the rare earth lanthanum can be used for relieving the harmof the acid rain stress to the Festuca elata, increasing the intracellular osmoregulation matters of the Festuca elata, restraining the peroxidation of cell membrane lipids, maintaining the stabilityof cell membranes, increasing the content of chlorophyll and enhancing the photosynthesis of the Festuca elata to accumulate photosynthetic products, so that the stress resistance of the Festuca elata is increased.