Thorax comforting drop pills for treating cardiopathy and preparation method thereof

A technique for dropping pills and relaxing chest, which is applied in the directions of cardiovascular system diseases, medical preparations containing active ingredients, and pill delivery, etc. and the effects of accelerated absorption, improved bioavailability, and increased total surface area

Inactive Publication Date: 2005-07-06
SHANDONG WOHUA PHARMACEUTICALS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0016] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0041] Now with several groups of specific examples, the preparation method of Shuxiong Dropping Pills of the present invention will be further described.

[0042] Group 1: Tests with a single matrix

[0043] 1. Weigh a certain amount of traditional Chinese medicine raw materials according to the ratio given in [Preparation Method] 1, and then prepare three kinds of active Chinese medicines containing Panax notoginseng, safflower and Chuanxiong according to the section [Appendix: Preparation method of a dry powder of traditional Chinese medicine]. The drug dry powder of the composition is ready for use;

[0044] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0045] 3. Proportion—take g or kg as the unit, in parts by weight, drug dry powder: matrix = 1:1~1:9;

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PUM

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Abstract

The invention relates to a medicinal oral preparation with the functions of promoting blood flow, wind expelling, relieving pain and treating coronary disease, angina pectoris, arrhythmia, extravasated blood and traumatic injury, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has blood circulation promoting, blood stasis dispelling and analgesic effects, and is used for treating blood stasis type coronary heart disease, angina pectoris, arrhythmia, blood stasis pain, traumatic injury etc. Tablets as the basis, a kind of pharmaceutical composition oral drop pill preparation formed by reforming the dosage form. Background technique [0002] According to the national drug standard WS 3 -Shuxiong Tablets prepared according to the formula and preparation process given in B-1247-92, is a kind of blood circulation promoting, blood stasis dispelling, pain relieving effect, used for the treatment of blood stasis type coronary heart disease, angina pectoris, arrhythmia, blood stasis Oral traditional Chinese medicine preparations for pain, bruises and other symptoms have been clinically verified to have stable quality and definite curative effect. [0003] The foll...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P9/06A61P9/10A61P19/00A61P29/00
Inventor 曲韵智
Owner SHANDONG WOHUA PHARMACEUTICALS CO LTD
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