Medicine composition for treating women's pulvic infection and its prepn process and use
A composition and technology for pelvic inflammatory disease, applied in the directions of drug combination, pharmaceutical formulation, drug delivery, etc., can solve the problems of gynecological pelvic inflammatory disease without Dahuang Mudan decoction, no industrialized production product, and inability to quickly reach the lesion site, etc. Effects of drug action time, improved bioavailability, prolonged residence and release time
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Embodiment 1
[0028] Embodiment 1 The preparation of medicinal material clear ointment of the present invention
[0029]1. Rhubarb and peony cortex are refluxed twice with 5-10 times the amount of 60-95% ethanol, each time for 0.1-1.5 hours. Combine the extracts, recover ethanol until it has no alcohol smell; or percolate with 5-15 times of 85-95% ethanol, recover the ethanol until it has no alcohol smell, and obtain the extract ①;
[0030] 2. Put peach kernels, wax gourd kernels, salvia miltiorrhiza, and Patrinia into 6-10 times boiling water, extract twice, decoct for 0.5-1.5 hours each time, filter the extract, concentrate the filtrate under reduced pressure, and obtain the extract ②;
[0031] 3. Combine extract ① and extract ②, stir evenly, and condense into a clear paste with a density of 1.10-1.40.
Embodiment 2
[0032] The preparation of embodiment 2 tablet for external use
[0033] 1. Common excipients for tablets are starch, soluble starch, lactose, magnesium stearate, dextrin, mannitol, sodium carboxymethyl starch, talcum powder, etc.
[0034] 2. Take clear ointment, add appropriate amount of commonly used excipients for tablets, granulate, dry, and compress into tablets.
[0035] By selecting different auxiliary materials, it can be made into vaginal tablets specified in the 2000 edition of "Chinese Pharmacopoeia", which can be ordinary tablets or effervescent tablets.
Embodiment 3
[0036] Example 3 Preparation of Effervescent Tablets for External Use
[0037] 1. Selection of excipients: common excipients for ordinary tablets, one or more of sodium bicarbonate, tartaric acid, citric acid, and fumaric acid.
[0038] 2. Preparation method:
[0039] (1) Take an appropriate amount of clear paste, add lactose and soluble starch, granulate, dry, and obtain ①;
[0040] (2) Sodium bicarbonate is dissolved in an appropriate amount of ethanol, and sprayed in a container containing ① through a sprayer to obtain ②;
[0041] (3) Tartaric acid and fumaric acid are granulated, dried, mixed evenly with ②, and pressed into tablets to obtain the product.
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