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Fig leaf extract and its use

A technology of fig leaves and extracts, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, antiviral agents, etc., to achieve wide application prospects, improve medicinal value and economic benefits, and widely inhibit and kill effects

Inactive Publication Date: 2005-08-10
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are no detailed reports at home and abroad on the experimental research on the anti-pathogenic microorganisms of fig leaf extracts

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment 1: Water extraction method prepares fig leaf extract

[0014] Put 20 grams of fig leaves (with stems) into a 500ml Erlenmeyer flask, add 200ml of double distilled water to soak overnight, filter, extract 3 times with water, remove the dregs, combine the filtrates for 3 times to a total of 400ml, and evaporate to 100ml in a 56°C water bath , the concentrated crude drug content is 60mg / ml, sterilized by suction filtration, divided into small bottles, and stored in a -20°C refrigerator for later use.

Embodiment 2

[0015] Embodiment 2: Ethanol extraction method prepares fig leaf extract

[0016] Soak the dried and broken fig leaves overnight in 95% ethanol, heat and reflux twice, combine the extracts, concentrate under reduced pressure, the crude drug content is 330mg / ml, filter and sterilize, divide into small bottles, and store in a -20°C refrigerator for later use. Dilute with Hank's buffer during experiment.

[0017] The fig leaf extracts obtained in Examples 1 and 2 were used to carry out anti-herpes simplex virus experiments and anti-common pathogenic bacteria experiments respectively. The specific methods and results are as follows.

[0018] 1. Anti-herpes simplex virus experimental method of fig leaf extract

[0019] 1. Cell Hep-2, BHK 21 and PRK three kinds of cells, Hep-2, and BHK 21 Quoted from the Sanitation and Epidemic Prevention Station of Shandong Province, all were subcultured with Eagle medium. The primary rabbit kidney cells (PRK) were obtained from suckling rabbits...

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PUM

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Abstract

An extract of fig leaf is prepared from the fig leaf through extracting in water or alcohol. Its can be used for preparing the medicines to kill the herpes simplex virus and the frequently encountered pathogenic bacteria.

Description

(1) Technical field [0001] The invention relates to a fig leaf extract and its application, belonging to the technical field of traditional Chinese medicine. (2) Background technology [0002] Fig (Ficus carica L) is a deciduous shrub or small tree of the genus Fig in the Moraceae family. It can be used as a green ornamental tree and edible. Its fruit is soft, sweet and delicious, rich in nutrition, contains a variety of vitamins and amino acids needed by the human body, as well as a large amount of dietary fiber, pectin, proteolytic enzymes, etc. Function. Fig leaves contain active ingredients such as psoralen, bergamot lactone, β-sitosterol, β-amyresinol and hopsyl alcohol-rich proteases, flavonoids, etc. The leaves also contain trace elements such as strontium, manganese, iron, copper, Zinc, selenium, cobalt, chromium, nickel, among which iron and zinc have the highest content. At the same time, the magnesium and calcium contents were also determined to be extremely hi...

Claims

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Application Information

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IPC IPC(8): A61P31/04A61P31/22
Inventor 王桂亭王志玉宋艳艳贾存显王皞许洪芝
Owner SHANDONG UNIV
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