Medication for treating cholecystitis and cholelithiasis, and preparation method

A cholecystitis and drug technology, applied in drug delivery, drug combination, medical formula, etc., can solve problems such as adverse surgical complications, lack of efficient drugs, and ineffective curative effect, so as to reduce dosage and side effects, and increase content , improve the effect of curative effect

Inactive Publication Date: 2005-08-31
健民集团叶开泰健康产业武汉有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is still a lack of efficient drugs for the treatment of this disease at home and abroad. Western medicine has only 30-60% effect on this disease, and has strong toxic and side effects; Unfavorable surgical complications occur;

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Grind the gardenia medicinal material into a coarse powder, extract 3 times with 70% ethanol under reflux, add 10 times the amount each time and extract for 1.5 hours, combine the extracts, recover the ethanol, and concentrate to the medicinal material:medicine solution=1:3, stand still, Centrifuge, discard the suspended solids and precipitates, take the treated polystyrene macroporous adsorption resin column on the centrifugate, first use 1.5 times the column volume to elute the impurities, and then use 2.5 times the column volume of 70% ethanol eluting, collecting the eluate, concentrating, and drying to obtain the iridoid glycoside extract. Get 177g of Gardenia iridoid glycosides extract (containing 133g of total iridoid glycosides), add appropriate amount of starch and magnesium stearate, adjust the total amount to 250g, mix well, divide into capsules and make 1000 capsules, namely Obtain the capsule dosage form of the present invention.

Embodiment 2

[0040] The gardenia iridoid glycoside extract powder was prepared according to the method in Example 1, and an appropriate amount of starch and magnesium stearate were added, mixed evenly, granulated, dried, and compressed into tablets to obtain a tablet dosage form.

Embodiment 3

[0042] The gardenia iridoid glycoside extract was prepared according to the method of Example 1, and fillers such as starch and microcrystalline cellulose, disintegrants such as sodium carboxymethyl starch, crospovidone, and low-substituted hydroxypropyl cellulose were added. and micropowder silica gel or magnesium stearate, mixed evenly, granulated, dried, and compressed into tablets to obtain dispersible tablets.

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PUM

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Abstract

A Chinese medicine in the form of capsule, tablet, dripping pile, injection, etc for treating cholecystitis and cholelithiasis is prepared from capejasmine fruit through extracting in water or alcohol, separating and purifying by macroreticular resin.

Description

technical field [0001] The invention relates to a medicine for treating cholecystitis and gallstone and a preparation method thereof, in particular to a traditional Chinese medicine preparation containing gardenia iridoid glycosides, which has good curative effect on the treatment of cholecystitis and gallstone , the invention also provides a preparation method of the medicine. Background technique [0002] Cholecystitis, gallstones are a kind of common disease, frequently-occurring disease of middle-aged and elderly people. Most cholecystitis is closely related to gallbladder stones, and about 95% of patients with chronic cholecystitis have stones at the same time. In recent years, the incidence of cholecystitis and cholelithiasis has been increasing year by year, especially in big cities. In addition, the incidence of obesity in middle-aged and elderly people has increased year by year. Due to the disorder of fat metabolism, the incidence of chol...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K9/20A61K9/48A61K31/7048A61P1/16
Inventor 熊富良黄志军石召华徐绍新李媛媛肖飞翟莉张雪琼袁铭
Owner 健民集团叶开泰健康产业武汉有限公司
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