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Prepn process and quality control technology of decoction of bupleurum root for regulating Shaoyang

A technology for decoction oral liquid and Bupleurum, applied in the field of traditional Chinese medicine preparation, can solve problems such as unreasonable preparation process, inconvenience, influence on the use of Xiao Chaihu Decoction, etc.

Inactive Publication Date: 2005-12-14
余世春
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  • Summary
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AI Technical Summary

Problems solved by technology

However, in China, Xiao Chai Hu Tang is usually prescribed by traditional Chinese medicine practitioners, and the patient prepares the medicine by himself, decocts it, and takes the liquid medicine, which is very inconvenient and affects the use of Xiao Chai Hu Tang.
In addition, there are Xiaochaihu decoction-like preparations replaced by Codonopsis ginseng, such as Xiaochaihu tablets and Xiaochaihu granules, but the preparation process is unreasonable, and there is no quantitative quality control method

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] Preparation method:

[0023] Take the prescription medicines that meet the requirements of the current edition of the Chinese Pharmacopoeia, add 8 times the amount of water to soak for 1 hour, distill twice, each time for 1 hour, collect the distillate, seal it, and refrigerate it for later use; Add 4 times the amount of water and decoct for half an hour, filter, combine the liquid medicine, concentrate to a relative density of 1.05-1.08 (heat measurement at 50°C), cool to room temperature, filter, alcohol precipitation, alcohol precipitation concentration 35%, refrigerated for 24 hours , filtered, the filtrate recovered ethanol and combined with the distillate, added 0.3% preservative and 0.5% stevioside, mixed well, adjusted the pH value to about 5.5, added water to adjust to the full amount, filtered, sterilized, and packaged to obtain .

[0024] The properties of Xiaochaihutang Oral Liquid are brown-red or brown liquid, with slightly fragrant gas and sweet a...

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Abstract

The present invention is preparation process and quality control technology of oral decoction liquid of bupleurum root for regulating Shaoyang. The recipe includes seven kinds of Chinese medicinal materials of bupleurum root, skullcap root, pinellia tuber, ginseng, ginger, licorice, etc; and the preparation process includes the steps of: soaking the materials in water and repeated distillation to collect the distillate; decocting the residue and merging decoction; cooling to room temperature, filtering, alcohol precipitation and recovering alcohol; merging the distillate and the concentrated liquid; adding proper amount of preservative, sweetener and water; filtering and sterilizing. The quality control includes the identification and content test of the effect components. The oral decoction liquid is superior to available corresponding decoction with taking inconvenience, lower bioavailability and inaccurate dosage.

Description

technical field [0001] The invention belongs to a preparation method of traditional Chinese medicine and its quality control technology. Background technique [0002] Xiao Chaihu Decoction comes from Zhang Zhongjing's "Treatise on Febrile Diseases" in the Eastern Han Dynasty. It is composed of Bupleurum, Scutellaria, Pinellia, Ginseng, Ginger, and Licorice. Symptoms such as fullness, hehe, no desire to eat, upset and vomiting, bitter mouth and dry throat, dizziness. [0003] Through systematic research on the mechanism of action of Xiaochaihu Decoction, it has been proved that this prescription has steroid-like and non-steroid-like anti-inflammatory effects, the pituitary-adrenal axis promotes and activates macrophages and T lymphocytes to enhance immunity, and can directly Act on the liver, protect the liver from damage, stimulate liver tissue regeneration, and inhibit the formation of liver fibrosis. [0004] The extract powder or granules of Xiaochaihu Decoction used cl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 余世春
Owner 余世春