Povidone iodine effervescence tablet for treating milk cow colpitis, its preparation process and application
A technology of povidone-iodine and vaginitis, which is applied in the field of veterinary drug preparation to achieve the effect of not causing drug resistance, fast onset, and increasing concentration
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Embodiment 1
[0034] Prepare 1000 kilograms of povidone-iodine effervescent tablets The physical addition of each component is as follows:
[0035] Povidone-iodine 80kg
[0036] Tartaric acid 200kg
[0037] Sodium bicarbonate 400kg
[0038] Cross-linked polyvinylpyrrolidone 100kg
[0039] Micropowder silica gel 20kg
[0040] Sodium Lauryl Sulfate 20kg
[0042] Lactose 175kg
[0043] It is prepared as follows:
[0044] (1) The components of the above formula are dried, passed through a 100 mesh sieve, and set aside;
[0045] (2) Take povidone-iodine, micropowder silica gel, sodium lauryl sulfate, lactose and cross-linked polyvinylpyrrolidone with half the amount of the above formula, fully mix with tartaric acid, and carry out dry granulation, Pass through a 20-mesh sieve to obtain A grain;
[0046] (3) Take povidone-iodine, micropowder silica gel, sodium lauryl sulfate, lactose and cross-linked polyvinylpyrrolidone with a quarter of the above-mention...
Embodiment 2
[0051] The amount of addition in kind of each component of preparing 1000 kilograms of pharmaceutical compositions is as follows:
[0052] Povidone-iodine 133kg
[0053] Tartaric acid 187.6kg
[0054] Sodium bicarbonate 375.2kg
[0055] Cross-linked polyvinylpyrrolidone 200kg
[0056] Micropowder silica gel 30kg
[0057]Sodium Lauryl Sulfate 20kg
[0058] Magnesium Stearate 10kg
[0059] Sodium chloride 44.2kg
[0060] It is prepared as follows:
[0061] (1) The components of the above formula are dried, passed through a 120 mesh sieve, and set aside;
[0062] (2) Take povidone-iodine, micropowder silica gel, sodium lauryl sulfate, sodium chloride and cross-linked polyvinylpyrrolidone with half of the above-mentioned formula amount, fully mix with tartaric acid and carry out dry method Granules were passed through a 16-mesh sieve to obtain A grains;
[0063] (3) Take povidone-iodine, micropowder silica gel, sodium lauryl sulfate, sodium chloride and cross-linked polyv...
Embodiment 3
[0068] The amount of addition in kind of each component of preparing 1000 kilograms of pharmaceutical compositions is as follows:
[0069] Povidone-iodine 326.8kg
[0070] Tartaric acid 163.5kg
[0071] Sodium bicarbonate 327kg
[0072] Cross-linked polyvinylpyrrolidone 100kg
[0073] Micropowder silica gel 30kg
[0074] Sodium Lauryl Sulfate 20kg
[0075] Magnesium Stearate 10kg
[0076] Lactose 22.7kg
[0077] It is prepared as follows:
[0078] (1) The components of the above formula are dried, passed through a 120 mesh sieve, and set aside;
[0079] (2) Take povidone-iodine, micropowder silica gel, sodium lauryl sulfate, lactose and cross-linked polyvinylpyrrolidone with half the amount of the above formula, fully mix with tartaric acid, and carry out dry granulation, Pass through a 16-mesh sieve to obtain A grain;
[0080] (3) Take povidone-iodine, micropowder silica gel, sodium lauryl sulfate, lactose and cross-linked polyvinylpyrrolidone with a quarter of the a...
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