Snowbell-leaf tickclover dripping pills and its preparation method

A technology of Desmodium stylifolia and grass dripping pills, which is applied in the field of Desmodium syringae dripping pills and its preparation, can solve the problems that are not conducive to improving the ability of patients to seek medical treatment, the bioavailability of the first-pass effect of the liver and intestines, and the overall health level, and achieve effective Conducive to labor protection and environmental protection, improve bioavailability, drug safety effect

Inactive Publication Date: 2006-02-08
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of Desmodium styracolii dripping pills of the present invention will be further described.

[0029] [recipe selection]

[0030] 1. Raw materials: According to the method provided in [Preparation Method 1], the dry powder of the drug extract containing the active ingredients of the traditional Chinese medicine Desmodium stylifolia is pre-prepared for use;

[0031] 2. Single matrix: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0032] 3. Combination matrix: take g or kg as the unit, by weight, choose polyethylene glycol, polyoxyl 40 stearate, sodium carboxymethyl starch, beta cyclodextrin, Tween and other carriers for combination test;

[0033] 3.1 The combination of two differen...

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PUM

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Abstract

The invention discloses a medicinal composition for treating urinary lithiasis, pyelonephritis and cholecystitis, especially snowbell-leaf tickclover dripping pills and its preparation method, wherein the dripping pills are prepared from snowbell-leaf tickclover, and medicinal carrying agent as the base material. The dripping pills have the advantages of high biological availability, quick-speed medicine release, quick-speed effect, higher medicinal content, easy administering, low price, and no contamination in production.

Description

technical field [0001] The invention relates to a pharmaceutical composition with the functions of clearing dampness and heat, diuresis and calculus expulsion, and is used for the treatment of urinary calculus, pyelonephritis, cholecystitis and other diseases caused by dampness and heat in the lower energizer. A pharmaceutical composition oral preparation. Background technique [0002] Shilintong granule, which is prepared according to the preparation method in the national drug standard WS-11044 (ZD-1044)-2002, is a kind of granule that has the functions of clearing away dampness and heat, diuresis and stone removal, and is used for urinary calculi and renal pelvis caused by dampness and heat in the lower Jiao. Oral granules for the treatment of nephritis, cholecystitis and other diseases have been clinically verified and have definite curative effects. They are commonly used drugs for clinical and family treatment of the above diseases. [0003] The following is the formu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61K9/20A61P13/04A61P13/12A61P1/16
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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