Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Use of morpholine methyltetralone in preparation of smooth muscles spasmolytic

A technology of morpholine methyltetralone and smooth muscle, which is applied in the field of medicine and can solve problems such as weak analgesic activity

Inactive Publication Date: 2010-09-08
SHENYANG PHARMA UNIVERSITY
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The results show that the compound has weak analgesic activity, but so far there is no report about the relaxing effect of CY on smooth muscle. The inventors have screened through various experiments and found that the compound has smooth muscle spasmolytic effect for the first time.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Use of morpholine methyltetralone in preparation of smooth muscles spasmolytic
  • Use of morpholine methyltetralone in preparation of smooth muscles spasmolytic
  • Use of morpholine methyltetralone in preparation of smooth muscles spasmolytic

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the use of CY in preparing smooth muscle spasmolysis agent, and in preparing medicaments for treating stomach and intestinal spasm colicky pain, intestine excitable syndrome, ulcerative colitis, stomach and intestine dysfunction, and functional diarrhea.

Description

Technical field: The invention relates to the technical field of medicine, in particular to the use of morpholine methyltetralone (CY) for preparing a smooth muscle antispasmodic agent. Background technique The chemical name of CY is morpholine methyltetralone (3,4-dihydro-2-(4-morpholinylmethyl)-1(2H)-naphthalenone), the compound in 1977 by Welch, Willard M.; Harbert, Charles A.; Sarges, Reinhard; Stratten, Wilford P. ; Weissman, et al successfully synthesized and investigated its analgesic activity. The results show that the compound has weak analgesic activity, but so far there is no report about the relaxing effect of CY on smooth muscle. The inventors found that the compound has antispasmodic effect on smooth muscle for the first time after various experimental screenings. The chemical system name of morpholine methyl tetralone is 2-(4-morpholine methyl)-1-tetralone, and its synthetic method is as follows Mix 4.20g (0.028mol) of 1-tetralone, 2.50g (0.029mol) of mo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61P13/12A61P1/12A61P1/16A61P11/06A61P13/08A61P13/04A61P1/00A61K31/535A61P13/10
Inventor 付守廷胡春魏巍刘晓平宋爱华
Owner SHENYANG PHARMA UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com