Acetyglutamide aluminium oral tablet, capsule and its preparing method

An aluminum acetylglutamine oral tablet, aluminum acetylglutamine technology, applied in capsule delivery, pill delivery, digestive system, etc.

Inactive Publication Date: 2006-08-09
王兰周
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after searching, there is no open technical literature on the preparation of aluminum acetylglutami

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation formula 1 of embodiment 1 aluminum acetylglutamine oral tablet

[0026] Aluminum Acetyl Glutamine 350g

[0027] Starch 20g

[0028] Lactose 10g

[0029] Microcrystalline Cellulose 8g

[0030] Carboxymethyl starch sodium 8g

[0031] Magnesium Stearate 2g

[0032] 60% ethanol 10g

[0033] Makes 1000 pieces

Embodiment 2

[0034] The preparation formula 2 of embodiment 2 acylglutamine aluminum oral tablet

[0035] Aluminum Acetylglutamine 233.3g

[0036] Povidone K30 5g

[0037] Microcrystalline Cellulose 5g

[0038] Sodium starch glycolate 5.7g

[0039] Magnesium Stearate 1g

[0040] 60% ethanol 8g

[0041] Makes 1000 pieces

Embodiment 3

[0042] The preparation formula of embodiment 3 aluminum acetylglutamine oral capsules

[0043] Aluminum Acetylglutamine 233.3g

[0044] Starch 5g

[0045] Microcrystalline Cellulose 5g

[0046] Sodium starch glycolate 6.7g

[0047] 60% ethanol 8g

[0048] Makes 1000 capsules

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PUM

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Abstract

The present invention belongs to a medicine preparation containing organic effective component, in particular, it relates to an acetyl-glutamine aluminium oral tablet or capsule preparation. Its composition contains (by weight portion) 200-400 portions of acetyl-glutamine, 0-30 portions of filling agent, 1-10 portions of moistening agent, 0-10 portions of adhesive, 0-10 portions of disintegrating agent and 0-10 portions of lubricating agent. Said invention also provides its preparation method and concrete steps.

Description

1. Technical field [0001] The invention belongs to pharmaceutical preparations containing organic active ingredients, in particular to tablets or capsules containing aluminum acetylglutamine and a preparation method thereof. 2. Background technology [0002] Aceglutamide aluminum (Aceglutamide aluminum), molecular formula: C 35 h 59 Al 3 N 10 o 24 , is an amorphous powder with an unpleasant bitter taste due to aluminum ions. [0003] Aluminum acetylglutamine has good preventive and therapeutic effects on various experimental ulcers. After oral administration, it adheres to the gastric mucosa to protect the gastric mucosa; it can generate hexosamine, which has the effects of antacid and pepsin resistance, and can also promote the repair of damaged mucosa; in addition, it can still inhibit gastric peristalsis. Clinically used to treat gastric and duodenal ulcers, the effect is remarkable. [0004] At present, the aluminum acetylglutamine listed abroad is only in the for...

Claims

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Application Information

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IPC IPC(8): A61K31/195A61K9/20A61K9/48A61P1/04
Inventor 王兰周江朝容
Owner 王兰周
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