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Blood fat-reducing medicine and its preparation method

A technology for lowering blood lipids and medicines, which is applied in the field of traditional Chinese medicine preparations for treating hyperlipidemia and the preparation technology thereof, and can solve the problems of no proof of curative effect and the like.

Inactive Publication Date: 2006-10-11
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no accurate proof of efficacy

Method used

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  • Blood fat-reducing medicine and its preparation method
  • Blood fat-reducing medicine and its preparation method
  • Blood fat-reducing medicine and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0098] The raw material composition of this embodiment is: perilla oil 421g soybean sterol 84g vitamin E 0.2g

[0099] Shell material: gelatin 250g, glycerin 125g, water 250g, ethylparaben 0.75g, purple iron oxide 2.75g

[0100] Its preparation method is:

[0101] a) Mix 125g of glycerin with 2.75g of purple iron oxide, and grind in a colloid mill to form an iron oxide suspension with uniform color. Then heat 250g of gelatin, 250g of water, 0.75g of ethylparaben and iron oxide suspension to 70°C, stir the gel, vacuumize to remove air bubbles, pass through a 400-mesh sieve, and transfer to a liquid storage tank at 64°C to keep warm for later use.

[0102] b), take by weighing 84g soybean sterol fine powder, mix with 421g perilla oil, 0.2g vitamin E, put in colloid mill and grind, medicinal liquid crosses 120 mesh sieves, becomes uniform oily suspension, transfers to the pill press Reserve in storage tank.

[0103] c) Adjust the temperature of the glue unfolding box to 54°C, ...

Embodiment 2

[0105] The raw material composition of this embodiment is: perilla oil 340g soybean sterol 165g vitamin E 2.5g shell material: gelatin 250g glycerin 125g water 200g ethylparaben 0.75g iron violet oxide 3.0g

[0106] a) Mix 125g of glycerin with 3.0g of purple iron oxide, and grind in a colloid mill to form an iron oxide suspension with uniform color. Then heat 250g of gelatin, 200g of water, 0.75g of ethylparaben and iron oxide suspension to 70°C, stir the gel, vacuumize to remove air bubbles, pass through a 400-mesh sieve, and transfer to a liquid storage tank at 66°C to keep warm for later use.

[0107] b), take by weighing 165g soybean sterol fine powder, mix with 340g perilla oil, 2.5g vitamin E, put in colloid mill and grind, medicinal liquid crosses 120 mesh sieves, becomes uniform oily suspension, transfers to the pill machine Reserve in storage tank.

[0108] c) Adjust the temperature of the glue unfolding box to 54°C, the mold loading to 0.5g / grain, the thickness of ...

Embodiment 3

[0111] The raw material composition of this embodiment is: perilla oil 460g soybean sterol 46g vitamin E0.5g

[0112] Shell material: gelatin 250g, glycerin 125g, water 250g, ethylparaben 0.5g, purple iron oxide 2.75g

[0113] The preparation method is as follows: a) Mix 125g of glycerin and 2.75g of purple ferric oxide, and grind in a colloid mill to form a ferric oxide suspension with uniform color and luster. Then heat 250g of gelatin, 250g of water, 0.5g of ethylparaben and iron oxide suspension to 70°C, stir to melt the gel, vacuumize to remove air bubbles, pass through a 400-mesh sieve, and transfer to a liquid storage tank to keep warm at 64°C for later use.

[0114] b), take by weighing 46g soybean sterol fine powder, mix with 460g perilla oil, 0.5g vitamin E, put in the colloid mill and grind, medicinal liquid crosses 120 mesh sieves, becomes uniform oily suspension, transfers to the pill machine Reserve in storage tank.

[0115] c) Adjust the temperature of the glu...

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Abstract

The invention relates to a Chinese medicinal preparation for lowering blood fat and its preparing process, wherein the preparation is a soft capsule using perilla oil and soyasterol as the active constituents, the preparing process consists of steps of mixing soyasterol and perilla oil with vitamin E, grinding homogeneously with colloid mill, finally making soft capsule.

Description

(1) Technical field [0001] The invention belongs to the technical field of blood lipid-lowering drugs, in particular to a traditional Chinese medicine preparation for treating hyperlipidemia and a preparation process thereof. (2) Background technology [0002] Hyperlipidemia is a common and frequently-occurring disease among middle-aged and elderly people, which seriously endangers human health and is the primary risk factor for arteriosclerosis, which in turn leads to cardiovascular and cerebrovascular diseases. Unsaturated fatty acid drugs have played a positive role in lowering blood lipids, such as Duoxekang capsules made from extracting EPA (eicosapentaenoic acid) and DHA (eicosahexaenoic acid) from fish oil, Evening primrose oil capsules made from gamma-linolenic acid extracted from primrose oil have good effects of lowering blood fat and inhibiting thrombus formation. But they all have some shortcomings to varying degrees. [0003] The content of EPA (eicosapentaeno...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/535A61K9/48A61K31/355A61K31/56A61P3/06
Inventor 李英霞武继彪张贞丽隋在云袁敏姜玉玫张希林
Owner SHANDONG ACAD OF CHINESE MEDICINE
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