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Blood replacing base liquid for blood purification treatment

A technology of blood replacement and blood purification, applied in the direction of blood diseases, extracellular fluid diseases, active ingredients of phosphorus compounds, etc., can solve problems such as high sugar and unfavorable sugar balance, so as to eliminate unevenness, facilitate storage and transportation, and ensure internal quality effect

Active Publication Date: 2006-11-08
CHENGDU QINGSHAN LIKANG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the components of blood replacement fluids reported so far are all composed of various ions, and generally do not contain glucose. Even if it needs to be added temporarily, the sugar content is generally high, which is obviously not conducive to the sugar balance in body fluids.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Take 3.825kg of anhydrous glucose, 13.200kg of sodium chloride, 0.324kg of magnesium chloride hexahydrate, 0.469kg of calcium chloride dihydrate, 0.700kg of potassium chloride, and 0.255kg of sodium dihydrogen phosphate, dissolve them in an appropriate amount of water for injection, and add an appropriate amount of activated carbon Stir, filter through a 0.45 μm titanium rod, add water for injection to a total volume of 2000 liters, filter through a 0.22 μm terminal filter, fill in PVC infusion bags, seal, and sterilize at 115 degrees Celsius for 30 minutes.

Embodiment 2

[0025] Take 3.825kg of anhydrous glucose, 13.200kg of sodium chloride, 0.324kg of magnesium chloride hexahydrate, 0.469kg of calcium chloride dihydrate, and 0.255kg of sodium dihydrogen phosphate. Stick filtration, add water for injection to a total volume of 2000 liters, filter through a 0.22 μm terminal filter, fill in PVC infusion bags, seal, and sterilize at 115 degrees Celsius for 30 minutes.

Embodiment 3

[0027] Take 3.825kg of anhydrous glucose, 13.200kg of sodium chloride, 0.324kg of magnesium chloride hexahydrate, and 0.469kg of calcium chloride dihydrate, dissolve them in an appropriate amount of water for injection, add an appropriate amount of activated carbon and stir, filter through a 0.45 μm titanium rod, and add water for injection to The total volume is 2000 liters, filtered through a 0.22 μm terminal filter, filled in PVC infusion bags, sealed, and sterilized at 115 degrees Celsius for 30 minutes.

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PUM

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Abstract

The blood replacing base liquid for blood purifying treatment contains Na, Ca, Mg and Cl ions in the normally physiological allowed range, glucose, K ion component and component capable of producing free phosphoric acid and similar matter. It is suitable for clinical personal use while regulating blood potassium level, ensuring the normal blood phosphorus level during the treatment, ensuring sugar balance and replenishing calorie loss. Compounding the blood replacing base liquid in mass production scale can well meet the clinical requirement and ensure the inherent quality of the blood replacing base liquid.

Description

technical field [0001] The invention relates to a blood replacement fluid for blood purification treatment, especially for continuous blood purification treatment. Background technique [0002] Blood purification therapy, especially continuous blood purification therapy, is one of the main treatment measures for critically ill patients today, and is as important as mechanical ventilation and total parenteral nutrition therapy. This technology can enable patients with multiple organ failure to undergo replacement therapy for renal or non-renal diseases smoothly. Acute respiratory distress syndrome (ARDS) and acute necrotizing pancreatitis play an increasingly important role. The technology mainly includes continuous venous-venous hemofiltration (CVVH); continuous arterial-venous hemodialysis (CAVHD) and continuous venous-venous hemodialysis (CVVHD); continuous arterial-venous hemodiafiltration (CAVHDF) And continuous veno-venous hemodiafiltration (CVVHDF); slow continuous u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/42A61K31/191A61K33/14A61P7/08
Inventor 唐万欣付平文艳秋刘先蓉陶冶杨炯王原
Owner CHENGDU QINGSHAN LIKANG PHARMA CO LTD
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